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Transferrin ( Tf ) and Group - specific Component ( Gc ) Variants in Korean Population
( Moon You Oh,Friedrich Kneppers,Chung Choo Lee ) 한국유전학회 1985 Genes & Genomics Vol.7 No.2
Some avriants of Transferrin and Group-specific Component have been investigated in Korean population by polyacrylamide gel isoelectric focusing. Among 1,085 unrelated individuals, 4 heterozygous transferrin variants. C1B1, C2B1, C2B1-2 and C2-variant, were detected. The numbers of each variant were 5(C1B1), 1(C2B1), 1(C2B1-2), and 1(C2-variant), respectively. The gene frequencies of the variants were; B1=0.0028, B1-2=0.00046, unknown variant=0.00046, respectively. On the other hand, among 1,227 unrelated individuals, 6 kinds of variants of Group-specific Component were detected, and their numbers were 2(1F-1A8), 2(2-1A9), 2(2-1A8), 1(2-1A12), 1(1S-1A9), 1(1A5-1A8), respectively. All of the variants were heterozygous only.