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Yu, Tao,Hou, Fenggang,Liu, Manman,Zhou, Lihong,Li, Dan,Liu, Jianrong,Fan, Zhongze,Li, Qi Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
The present study was based on the unexpected discovery that norcantharidin exerted anti-angiogenesis activity when effects on growth of human colon cancer were studied. The aim was to further verify this finding and explore possible mechanisms using a tumor xenograft model in nude mice. We confirmed that norcantharidin (5 or 15 mg/kg) could inhibit angiogenesis of human colon cancer in vivo. In vitro, crossing river assay, cell adhesion assay and tube formation assay indicated that NCTD could reduce the migration, adhesion and vascular network tube formation ability of HUVECs. At the same time, the expression levels of VEGF and VEGFR-2 proteins which play important roles in angiogenesis were reduced as examined by western blotting analysis. Taken together, the results firstly showed NCTD could inhibit angiogenesis of human colon cancer in vivo, probably associated with effects on migration, adhesion and vascular network tube formation of HUVECs and expression levels of VEGF and VEGFR-2 proteins.
Fei Liu,Bing-Bing Li,De Sun,Fenggang Li,Xinyue Pei 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.5
Membrane hydrophilicity is a crucial factor in evaluating ultrafiltration processes. In this paper, chitosan(CS) was selected for the hydrophilic modification of the polylactic acid (PLA) membrane, and PLACS membranes wereprepared for the densification of the yeast solution. By non-solvent phase inversion method (NIPS), the PLACS microfiltrationmembranes were prepared by using chitosan (CS) acetic acid solution as the coagulation bath and glutaraldehydeas the crosslinking agent. PLACS membranes were characterized by water contact angle, porosity, pore sizedistribution, mechanical properties, ATR-FTIR, SEM, TGA and the ultrafiltration experiment. The viscosity of coagulationbath solution can severely influence the exchange rate of the solvent and the non-solvent as well during phaseinversion; therefore, it can regulate the precipitation kinetics and membrane morphology. The results showed that chitosan(CS) was presented as granular on the pore surfaces of the PLACS membranes. When chitosan (CS) contentincreased, gel rate became smaller and membrane forming process was prolonged; the porosity and pore size of thePLACS were increased compared to the polylactic acid (PLA) membrane, pure water flux increased from 90.31 L·m2·h1to 120.14 L·m2·h1, and yeast rejection rate increased from 75% to more than 90%.
Accelerated Split Bregman Method for Image Compressive Sensing Recovery under Sparse Representation
( Bin Gao ),( Peng Lan ),( Xiaoming Chen ),( Li Zhang ),( Fenggang Sun ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.6
Compared with traditional patch-based sparse representation, recent studies have concluded that group-based sparse representation (GSR) can simultaneously enforce the intrinsic local sparsity and nonlocal self-similarity of images within a unified framework. This article investigates an accelerated split Bregman method (SBM) that is based on GSR which exploits image compressive sensing (CS). The computational efficiency of accelerated SBM for the measurement matrix of a partial Fourier matrix can be further improved by the introduction of a fast Fourier transform (FFT) to derive the enhanced algorithm. In addition, we provide convergence analysis for the proposed method. Experimental results demonstrate that accelerated SBM is potentially faster than some existing image CS reconstruction methods.