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        Mushroom varieties found in the Himalayan regions of India: Antioxidant, antimicrobial, and antiproliferative activities

        Khan, Asma Ashraf,Gani, Adil,Ahmad, Mudasir,Masoodi, Farooq Ahmad,Amin, Furheen,Kousar, Shaheen 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.4

        This study evaluates the antioxidant, antimicrobial, and antiproliferative activities of mushroom varieties (Agaricus bisporus, Pleurotus ostreatus, and Coprinus atramentarius) found in the Himalayan regions of Jammu and Kashmir, India. All three mushroom varieties exhibited antioxidant activity. A. bisporus showed the highest diphenyl-2-picrylhydrazyl inhibition activity ($87.88{\pm}5.6%$), C. atramentarius showed the highest reducing power ($0.49{\pm}0.01$) and metal chelating ability ($48.57{\pm}0.38%$), and P. ostreatus contained the highest phenolic ($5.25{\pm}0.14mg$ gallic acid equivalent per gram) and flavonoid content ($64.39{\pm}0.73{\mu}g$ rutin equivalent per gram). C. atramentarius showed maximum antibacterial activity against all the pathogenic strains and the highest zone of inhibition was against S. typhi ($7.45{\pm}0.5mm$). P. ostreatus exhibited the highest cell proliferation inhibition against Colo-205 and MCF-7 cancer cell lines. The structural analysis by Fourier transform infrared spectroscopy indicated the presence of ${\beta}-configuration$ in carbohydrates, phenolic compounds, and protein, which impart nutraceutical properties to mushrooms.

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        Mushroom varieties found in the Himalayan regions of India: Antioxidant, antimicrobial, and antiproliferative activities

        Asma Ashraf Khan,Adil Gani,Mudasir Ahmad,Farooq Ahmad Masoodi,Furheen Amin,Shaheen Kousar 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.4

        This study evaluates the antioxidant, antimicrobial, and antiproliferative activities ofmushroom varieties (Agaricus bisporus, Pleurotus ostreatus, and Coprinus atramentarius) found in theHimalayan regions of Jammu and Kashmir, India. All three mushroom varieties exhibited antioxidantactivity. A. bisporus showed the highest diphenyl-2-picrylhydrazyl inhibition activity (87.88±5.6%), C. atramentarius showed the highest reducing power (0.49±0.01) and metal chelating ability (48.57±0.38%), and P. ostreatus contained the highest phenolic (5.25±0.14 mg gallic acid equivalent per gram)and flavonoid content (64.39±0.73 μg rutin equivalent per gram). C. atramentarius showed maximumantibacterial activity against all the pathogenic strains and the highest zone of inhibition was against S. typhi (7.45±0.5 mm). P. ostreatus exhibited the highest cell proliferation inhibition against Colo-205and MCF-7 cancer cell lines. The structural analysis by Fourier transform infrared spectroscopyindicated the presence of β-configuration in carbohydrates, phenolic compounds, and protein, whichimpart nutraceutical properties to mushrooms.

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