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Menglin Zhu,Jing Gu,Lili He,Faraz Khan Mahar,김익수,Kai Wei 한국섬유공학회 2019 Fibers and polymers Vol.20 No.9
In this work, regenerated silk fibroin (SF)/poly-L-lactic acid (PLLA) composite electrospun fibers weresuccessfully prepared by electrospinning method with single and double syringe systems. Furtherly, we applied simultaneousand alternative spinning when using double syringe systems. The morphologies of the obtained silk/PLLA hybrid nanofiberswere characterized by scanning electron microscope (SEM). Fourier transform infrared spectroscopy (FTIR) showed thatPLLA has been well incorporated into the SF electrospun fibers using double syringes. Furthermore, the tensile test resultsindicate the tensile strength and Young’s modulus of the silk/PLLA hybrid nanofibers webs were improved by both singleand double syringe system. Moreover, the cell adhesion ratios of simultaneous silk/PLLA nanofibers were much higher thanthat of alternative silk/PLLA nanofibers, and even higher than pure silk nanofibers. Therefore, simultaneous spinning usingdouble syringe system is a potential method for fabrication of nanofiber scaffold.