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Fakhrul Islam,Sofiyan Saleem,Muzamil Ahmad,Abdullah Shafique Ahmad,Seema?ousuf,Mubeen Ahmad Ansari,M. Badruzzaman Khan,Tauheed Ishrat 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.4
The objective of the present study was to investigate the effects of aqueous garlic extract (AGE) on neurobe-havioral activities, malondialdehyde (MDA) and reduced glutathione (GSH) levels, glutathione peroxidase (GPx), glutathionereductase (GR), glutathione S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), and sodium-potassium ATPase (Na. ,K. -ATPase) activities, and glutamate and aspartate content in a middle cerebral artery (MCA) occlusion(MCAO) model of acute cerebral ischemia in rats. The right MCA of male Wistar rats was occluded for 2 hours using intra-luminal 4-0 monofilament, and reperfusion was allowed for 22 hours. MCAO caused significant depletion in GSH and its dependent enzymes (GPx, GR, and GST) and significant elevation of MDA, glutamate, and aspartate. The activities of Na. ,K. -ATPase, SOD, and CAT were decreased significantly by MCAO. The neurobehavioral activities (grip strength, spontaneousmotor activity, and motor coordination) were also decreased significantly in the MCAO group. All of the alterations inducedby ischemia were significantly attenuated by pretreatment with AGE (500 mg/mL/kg of body weight, i.p.) 30 minutes beforethe induction of MCAO and correlated well with histopathology by decreasing the neuronal cell death following MCAO andreperfusion. These findings suggest that AGE effectively modulates neurobehavioral and neurochemical changes in focal is-chemia, most probably by virtue of its antioxidant properties.
Fakhrul Islam,Sofiyan Saleem,Muzamil Ahmad,Abdullah Shafique Ahmad,Seema Yousuf,Mubeen Ahmad Ansari,M. Badaruzzaman Khan,Tauheed Ishrat 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.2
The modifying effects of Crocus sativus(CS) stigma extract on neurobehavioral activities, malondialdehyde(MDA), reduced glutathione (GSH), glutathione peroxidase, glutathione reductase, glutathione S-transferase, superoxide dis-mutase (SOD), catalase (CAT), and Na. ,K. -ATPase activities, and glutamate (Glu) and aspartate (Asp) content were exam-ined in the middle cerebral artery (MCA) occlusion (MCAO) model of acute cerebral ischemia in rats. The right MCA ofmale Wistar rats was occluded for 2 hours using intraluminal 4-0 monofilament, and reperfusion was allowed for 22 hours.MCAO caused significant depletion in the contents of GSH and its dependent enzymes while significant elevation of MDA,Glu, and Asp. The activities of Na. ,K. -ATPase, SOD, and CAT were decreased significantly by MCAO. The neurobehav-ioral activities (grip strength, spontaneous motor activity, and motor coordination) were also decreased significantly in theMCAO group. All the alterations induced by ischemia were significantly attenuated by pretreatment of CS (100 mg/kg ofbody weight, p.o.) 7 days before the induction of MCAO and correlated well with histopathology by decreasing the neuronalcell death following MCAO and reperfusion. The present results may suggest the effectiveness of CS in focal ischemia mostprobably by virtue of its antioxidant property.
Hossain, M.I.,Momin, M.M.,Fakhrul Islam, K.M.,Quader, M.N.,Miah, G. The Korean Society of Embryo Transfer 2016 한국동물생명공학회지 Vol.31 No.3
It is imperious to know the reproductive parameters of the subsisting swine breed for profitable farming in Bangladesh. This study was designed to compare the reproductive parameters of sows at hilly areas between the local and crossbred at farm and backyard level. A total of 116 breedable sows were included. The data on age at puberty, litter size, birth weight, weaning weight, gestation length, interval between farrowing and number of piglets born per sow in local and crossbred sows were determined and direct questionnaire method was used for data collection. The present study revealed that age at puberty between farm and backyard system of crossbred sows was $8.88{\pm}0.153$ and $9.85{\pm}0.221$ months, respectively. The farrowing interval was shorter in crossbred sows which were kept in farming system rather than backyard system. The interval between farrowing and onset of estrus was shorter in crossbred sows. The gestation length was almost similar between backyard and farm condition. The number of litter size per sow per farrowing was $8.45{\pm}0.41$ in crossbred and $7.17{\pm}0.250$ in local pigs at backyard system. The birth weight and weaning weight were more in farm conditions than backyard system. The age at puberty in local breed was lower than the crossbred and litter size was $8.45{\pm}0.407$ in crossbred which was higher than local breed $7.17{\pm}0.250$ in backyard system. These results suggest that reproductive parameters of local sow need to be improved for better production and crossbred sows should be reared for obtaining desired productivity.
M.I. Hossain,M.M. Momin,K.M. Fakhrul Islam,M.N. Quader,G. Miah 한국수정란이식학회 2016 한국동물생명공학회지 Vol.31 No.3
It is imperious to know the reproductive parameters of the subsisting swine breed for profitable farming in Bangladesh. This study was designed to compare the reproductive parameters of sows at hilly areas between the local and crossbred at farm and backyard level. A total of 116 breedable sows were included. The data on age at puberty, litter size, birth weight, weaning weight, gestation length, interval between farrowing and number of piglets born per sow in local and crossbred sows were determined and direct questionnaire method was used for data collection. The present study revealed that age at puberty between farm and backyard system of crossbred sows was 8.88±0.153 and 9.85±0.221 months, respectively. The farrowing interval was shorter in crossbred sows which were kept in farming system rather than backyard system. The interval between farrowing and onset of estrus was shorter in crossbred sows. The gestation length was almost similar between backyard and farm condition. The number of litter size per sow per farrowing was 8.45±0.41 in crossbred and 7.17±0.250 in local pigs at backyard system. The birth weight and weaning weight were more in farm conditions than backyard system. The age at puberty in local breed was lower than the crossbred and litter size was 8.45±0.407 in crossbred which was higher than local breed 7.17±0.250 in backyard system. These results suggest that reproductive parameters of local sow need to be improved for better production and crossbred sows should be reared for obtaining desired productivity.