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        Comparative assessment of antibacterial activity of different glass ionomer cements on cariogenic bacteria

        Naik, Rahul Gaybarao,Dodamani, Arun Suresh,Khairnar, Mahesh Ravindra,Jadhav, Harish Chaitram,Deshmukh, Manjiri Abhay The Korean Academy of Conservative Dentistry 2016 Restorative Dentistry & Endodontics Vol.41 No.4

        Objectives: Glass ionomer cements (GICs), which are biocompatible and adhesive to the tooth surface, are widely used nowadays for tooth restoration. They inhibit the demineralization and promote the remineralization of the tooth structure adjacent to the restoration, as well as interfere with bacterial growth. Hence, the present study was conducted to assess and compare the antimicrobial activity of three commercially available GICs against two cariogenic bacteria. Materials and Methods: An agar plate diffusion test was used for evaluating the antimicrobial effect of three different GICs (Fuji IX, Ketac Molar, and d-tech) on Streptococcus mutans (S. mutans) and Lactobacillus acidophilus (L. acidophilus). Thirty plates were prepared and divided into two groups. The first group was inoculated with S. mutans, and the second group was inoculated with L. acidophilus. These plates were then incubated at $37^{\circ}C$ for 24 hours. Zones of bacterial growth inhibition that formed around each well were recorded in millimeters (mm). Results: The zones of inhibition for Fuji IX, Ketac Molar, and d-tech on S. mutans were found to be $10.84{\pm}0.22mm$, $10.23{\pm}0.15mm$, and $15.65{\pm}0.31mm$, respectively, whereas those for L. acidophilus were found to be $10.43{\pm}0.12mm$, $10.16{\pm}0.11mm$, and $15.57{\pm}0.13mm$, respectively. Conclusions: D-tech cement performed better in terms of the zone of bacterial inhibition against the two test bacteria, than the other two tested glass ionomers.

      • KCI등재

        Comparative assessment of antibacterial activity of different glass ionomer cements on cariogenic bacteria

        Rahul Gaybarao Naik,Arun Suresh Dodamani,Mahesh Ravindra Khairnar,Harish Chaitram Jadhav,Manjiri Abhay Deshmukh 대한치과보존학회 2016 Restorative Dentistry & Endodontics Vol.41 No.4

        Objectives: Glass ionomer cements (GICs), which are biocompatible and adhesive to the tooth surface, are widely used nowadays for tooth restoration. They inhibit the demineralization and promote the remineralization of the tooth structure adjacent to the restoration, as well as interfere with bacterial growth. Hence, the present study was conducted to assess and compare the antimicrobial activity of three commercially available GICs against two cariogenic bacteria. Materials and Methods: An agar plate diffusion test was used for evaluating the antimicrobial effect of three different GICs (Fuji IX, Ketac Molar, and d-tech) on Streptococcus mutans (S. mutans) and Lactobacillus acidophilus (L. acidophilus). Thirty plates were prepared and divided into two groups. The first group was inoculated with S. mutans, and the second group was inoculated with L. acidophilus. These plates were then incubated at 37℃ for 24 hours. Zones of bacterial growth inhibition that formed around each well were recorded in millimeters (mm). Results: The zones of inhibition for Fuji IX, Ketac Molar, and d-tech on S. mutans were found to be 10.84 ± 0.22 mm, 10.23 ± 0.15 mm, and 15.65 ± 0.31 mm, respectively, whereas those for L. acidophilus were found to be 10.43 ± 0.12 mm, 10.16 ± 0.11 mm, and 15.57 ± 0.13 mm, respectively. Conclusions: D-tech cement performed better in terms of the zone of bacterial inhibition against the two test bacteria, than the other two tested glass ionomers.

      • KCI등재

        Design, synthesis and pharmacological analysis of 5-[40- (substituted-methyl)[1,10-biphenyl]-2-yl]-1H-tetrazoles

        Atulkumar Kamble,Ravindra Kamble,Suneel Dodamani,Sunil Jalalpure,Vijaykumar Rasal,Mahadev Kumbar,Shrinivas Joshi,Sheshagiri Dixit 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.4

        In the present paper 5-[40-({4-[(4-aryloxy)methyl]-1H-1,2,3-triazol-1-yl}methyl)[1,10-biphenyl]-2-yl]-1H-tetrazoles(5a–g) and [20 -(1H-tetrazol-5-yl)[1,10-biphenyl]-4-yl]methyl-substituted-1-carbodithioates (11h–q) havebeen designed and synthesized. These compounds weresubjected to docking (against AT1 receptor proteinenzyme in complex with Lisinopril), in vitro angiotensinconverting enzyme inhibition, anti-proliferative, anti-inflammatoryscreening (through egg albumin denaturationinhibition and red blood cell membrane stabilizationassay) and finally anti-fungal activity analyses. Some ofthe compounds have shown significant pharmacologicalproperties.

      • KCI등재

        Comparison of Meteorological Drought Indices for Different Climatic Regions of an Indian River Basin

        Abhishek A. Pathak,B. M. Dodamani 한국기상학회 2020 Asia-Pacific Journal of Atmospheric Sciences Vol.56 No.4

        Droughts being a regional phenomenon has a vicious impact on agricultural production as well as on the socioeconomic status of an area. Meteorological drought is not only the result of rainfall deficit but also influenced by temperature in the form of evapotranspiration. There are several indices that could assess meteorological drought. Because of the complex phenomenon underling in the interaction between climatic, hydrological and ecological variables hampers to ascertain the suitability of a drought index to a particular region. The present work aims to compare different meteorological drought indices for a given climatic condition at the regional level. The Standardized Precipitation Index (SPI), Reconnaissance Drought Index (RDI) and Standardized Precipitation Evapotranspiration Index (SPEI) were employed to study the variation of drought characteristics calculated from these indices. The study was implemented in the Ghataprabha river basin, which is one of the potential lands for agriculture in the basin of river Krishna. The study area possesses negative trends in rainfall and significant increasing trends in the temperature when tested with the Mann-Kendell trend test. Several drought events were observed through SPI, RDI, and SPEI over the basin. SPEI identified the highest number of drought events with high duration and severe intensity as compared to SPI and RDI. The alike performance was noticed between RDI and SPI whereas SPEI does not harmonize with them at any timescale of the study period. The study recommends to consider RDI and SPI in the humid (subhumid) region and SPEI at the semiarid (arid) region to assess the impact of drought effectively. The study also suggests to use an appropriate drought index for analysis of drought, which could lead to an adequate preparedness for the future drought hazards.

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