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- 저자 : Chun-xi Ge (검색결과 2 건)
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Long-term monitoring of super-long stay cables on a cable-stayed bridge
Xiang Shen,Ru-jin Ma,Chun-xi Ge,Xiao-hong Hu 한국풍공학회 2018 Wind and Structures, An International Journal (WAS Vol.27 No.6
For a long cable-stayed bridge, stay cables are its most important load-carrying components. In this paper, long-term monitoring of super-long stay cables of Sutong Bridge is introduced. A comprehensive data analysis procedure is presented, in which time domain and frequency domain based analyses are carried out. In time domain, the vibration data of several long stay cables are firstly analyzed and the standard deviation of the acceleration of stay cables, and its variation with time are obtained, as well as the relationship between in-plane vibration and out-plane vibration. Meanwhile, some vibrations such as wind and rain induced vibration are detected. Through frequency domain analysis, the basic frequencies of the stay cables are identified. Furthermore, the axial forces and their statistical parameters are acquired. To investigate the vibration deflection, an FFT-based decomposition method is used to get the modal deflection. In the end, the relationship between the vibration amplitude of stay cables and the wind speed is investigated based on correlation analysis. Through the adopted procedure, some structural parameters of the stay cables have been derived, which can be used for evaluating the component performance and corresponding management of stay cables.
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Dynamic analysis for gene expression profiles of endothelial colony forming cells under hypoxia
De-Cai Yu,Wen-Du Feng,Xian-Biao Shi,hi-Yong Wang,Wei Ge,Chun-Ping Jiang,Xi-Tai Sun,Yi-Tao Ding 한국유전학회 2013 Genes & Genomics Vol.35 No.4
Previous studies have shown that endothelial colony forming cells (ECFCs) play an important role in the neovascularization of tumors. Hypoxia is emphasized as an important promoter of angiogenesis. However, little is known about genome-wide transcriptional regulation of ECFCs under hypoxic conditions. In this study, gene expression profiles in ECFCswere evaluated under hypoxic conditions for 3, 6, 12, 24,and 48 h, using Affymetrix U133 plus 2.0 chip microarray. 1,103 hypoxia-regulated genes were filtered, with 379(0.693 %) genes up-regulated and 724 (1.32 %) genes downregulated. Most of the up-regulated genes were involved in apoptosis, cell proliferation, or metabolic processes, while most of the down-regulated genes were involved in cell adherence,cell cycle,DNAandmRNAmetabolic processes,multi-cellular organism development, protein metabolic processes, response to stress, signal transduction, or transport. This expression profile is ECFC-specific, because it is significantly different from those of endothelial cells and smooth muscle cells under hypoxic conditions. Moreover, hypoxia-regulated apoptosis in ECFCs is mainly related with the mitochondrial pathway (p53-BAX-Caspase-9) and the death receptor pathway (FASCaspase-8-Caspase-3). MAPK pathway is activated in ECFCs under hypoxic conditions. The differentially expressed genes of ECFCs were identified under hypoxic conditions, and related with cell apoptosis, cell cycle and MAPK pathways, shedding light on the mechanism of angiogenesis.
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