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RISS 인기검색어
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- 저자 : Chiani, Mohsen (검색결과 5 건)
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MIMO Networks: The Effects of Interference
Chiani, M.,Win, M.Z.,Hyundong Shin IEEE 2010 IEEE transactions on information theory Vol.56 No.1
<P>Multiple-input multiple-output (MIMO) systems are being considered as one of the key enabling technologies for future wireless networks. However, the decrease in capacity due to the presence of interferers in MIMO networks is not well understood. In this paper, we develop an analytical framework to characterize the capacity of MIMO communication systems in the presence of multiple MIMO co-channel interferers and noise. We consider the situation in which transmitters have no channel state information, and all links undergo Rayleigh fading. We first generalize the determinant representation of hypergeometric functions with matrix arguments to the case when the argument matrices have eigenvalues of arbitrary multiplicity. This enables the derivation of the distribution of the eigenvalues of Gaussian quadratic forms and Wishart matrices with arbitrary correlation, with application to both single-user and multiuser MIMO systems. In particular, we derive the ergodic mutual information for MIMO systems in the presence of multiple MIMO interferers. Our analysis is valid for any number of interferers, each with arbitrary number of antennas having possibly unequal power levels. This framework, therefore, accommodates the study of distributed MIMO systems and accounts for different spatial positions of the MIMO interferers.</P>
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MIMO Capacity, Level Crossing Rates and Fades: The Impact of Spatial/Temporal Channel Correlation
Giorgetti, Andrea,Smith, Peter J.,Shafi, Mansoor,Chiani, Marco The Korea Institute of Information and Commucation 2003 Journal of communications and networks Vol.5 No.2
It is well known that Multiple Input Multiple Output (MIMO) systems offer the promise of achieving very high spectrum efficiencies (many tens of bit/s/Hz) in a mobile environment. The gains in MIMO capacity are sensitive to the presence of spatial and temporal correlation introduced by the radio environment. In this paper, we examine how MIMO capacity is influenced by a number of factors e.g., a) temporal correlation b) various combinations of low/high spatial correlations at either end, c) combined spatial and temporal correlations. In all cases, we compare the channel capacity that would be achievable under independent fading. We investigate the behaviour of "capacity fades," examine how often the capacity experiences the fades, develop a method to determine level crossing rates and average fade durations and relate these to antenna numbers. We also evaluate the influence of channel correlation on the capacity autocorrelation and assess the fit of a Gaussian random process to the temporal capacity sequence. Finally we note that the particular spatial correlation structure of the MIMO channel is influenced by a large number of factors. For simplicity, it is desirable to use a single overall correlation measure which parameterizes the effect of correlation on capacity. We verify this single parameter concept by simulating a large number of different spatially correlated channels.
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Amiri, Boshra,Ebrahimi-Far, Meysam,Saffari, Zahra,Akbarzadeh, Azim,Soleimani, Esmaeil,Chiani, Mohsen Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.8
Background: Breast cancer is one of the most frequent cancer types within female populations. Silibinin is a chemotherapeutic agent ative against cancer. Niosomes are biodegradable, biocompatible, safe and effective carriers for drug delivery. Objective:To prepare nanoniosomal silibinin and evaluate its cytotoxicity inthe T-47D breast cancer cell line. Materials and Methods: Niosomes were prepared by reverse phase evaporation of a mixture of span 20, silibinin, PEG-2000 and cholesterol in chloroform and methanol solvent (1:2 v/v). The solvent phase was evaporated using a rotary evaporator and the remaining gel phase was hydrated in phosphate buffer saline. Mean size, size distribution and zeta potential of niosomes were measured with a Zetasizer instrument and then nanoparticles underwent scanning electron microscopy. The drug releasing pattern was evaluated by dialysis and the cytotoxicity of nanoniosomes in T-47D cells was assessed by MTT assay. Results: Particle size, size variation and zeta potential of the niosomal nanoparticles were measured as $178.4{\pm}5.4nm$, $0.38{\pm}0.09$ and $-15.3{\pm}1.3mV$, respectively. The amount of encapsulated drug and the level of drug loading were determined $98.6{\pm}2.7%$ and $22.3{\pm}1.8%$, respectively; released drug was estimated about $18.6{\pm}2.5%$ after 37 hours. The cytotoxic effects of nanoniosome were significantly increased when compared with the free drug. Conclusions: This study finding suggests that silibinin nanoniosomes could serve as a new drug formulation for breast cancer therapy.
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Elnaz Asgharkhani,Anahita Fathi Azarbayjani,Shiva Irani,Mohsen Chiani,Zahra Saffari,Dariush Norouzian,Azim Akbarzadeh,Seyed Mohammad Atyabi 한국약제학회 2018 Journal of Pharmaceutical Investigation Vol.48 No.3
Artemisinin (ART)-loaded niosome and pegylated niosomes were prepared using two different techniques. Nanosized lipid vesicles were physically characterized for entrapment efficacy and stability. Particle sizes were determined and release kinetic of the optimized formulation was carried out by dialysis method. The efficacy of the developed formulation was tested on MCF7 cells and cytotoxicity was accomplished by MTT assay. Common observation was the effect of pegylation on the reduction of vesicle size due to its hydrophilic nature. Span 60 niosomes had slightly larger vesicle size than Span 20 niosomes. Over all the good stability was observed over 60 days. In vitro drug release studies indicate gradual release of niosome over 40 h. similar trend in drug release was observed for most formulation except for the multilammellar pegylated niosomes. Pegylation of niosomes causes increased stability and efficacy of ART. Cytotoxicity ( IC50) was evaluated at different time of incubation at 48 and 72 h for selected niosomal formulations. Pegylated ART niosomes show great advantages in term of interaction with MCF-7 cell membrane. Results suggest that pegylated niosomes may be an appropriate candidate for the clinical administration of ART.
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