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- 저자 : Chen ZhaoZhao (검색결과 2 건)
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Feng Chen,Shiqi Jiang,Dianheng Jin,Zhaozhao Mei 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.2
Output filter is an essential part of a grid-connected inverter used for improving the quality of a grid-injected current. The use of LCL filters in power converters in microgrid applications is more preferred compared with L or LC filters because of their better harmonic attenuation capability. However, LCL filter still occupies a main part of the weight and volume of the whole system. Thus, more progress can be further developed with this consideration. In this paper, based on a 2.5 kW threephase voltage source inverter, a magnetic-integrated LCL filter is designed by sharing an EIE-type core to reduce weight and size significantly. With the magnetic coupling influence taken into consideration, more effective design principles of the filter are discussed according to theoretical analysis and mathematical modeling. Meanwhile, a double closed-loop control strategy is utilized to eliminate the resonance introduced by the LCL filter and stabilize the system. Simulation and practical experiments are conducted with a detailed comparison between the discrete and integrated LCL filters, which can verify the feasibility and validity of the proposed method.
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Zhou Jie,Xu Min,Chen ZhaoZhao,Huang LinLin,Wu ZhuoLin,Huang ZhongPei,Liu Lin 한국조직공학과 재생의학회 2023 조직공학과 재생의학 Vol.20 No.7
BACKGROUND: This study aims to explore the potential mechanism of action of the newly discovered hsa_- circ_0128899 (circSPEF2) in diffuse large B-cell lymphoma (DLBCL). METHODS: circSPEF2, miR-16-5p and BTB and CNC homologue 2 (BACH2) expression patterns in DLBCL patients and cell lines were studied by RT-qPCR. The biological function of circSPEF2 in vitro and in vivo was investigated by function acquisition experiments. The proliferation activity of lymphoma cells was detected by MTT. Bax, Caspase-3, and Bcl-2 were determined by Western Blot. Apoptosis and the ratio of CD4 to Treg of immune cells in the co-culture system were analyzed by flow cytometry. The mechanism of action of circSPEF2 in DLBCL progression was further investigated by RIP and dual luciferase reporter experiments. RESULTS: circSPEF2 was a circRNA with abnormally down-regulated expression in DLBCL. Increasing circSPEF2 expression inhibited the proliferative activity and induced apoptosis of lymphoma cells in vitro and in vivo, as well as increased CD4?T cells and decreased Treg cell proportion of immune cells in the tumor microenvironment. Mechanically, circSPEF2 was bound to miR-16-5p expression, while BACH2 was targeted by miR-16-5p. circSPEF2 overexpressionmediated effects on lymphoma progression were reversible by upregulating miR-16-5p or downregulating BACH2. CONCLUSIONS: circSPEF2 can influence DLBCL progression by managing cellular proliferation and apoptosis and the proportion of immune cells Treg and CD4 through the miR-16-5p/BACH2 axis.
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