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Bian, L.,Chung, H.J. IRL Press 2016 Food hydrocolloids Vol.60 No.-
<P>The impact of single and dual hydrothermal treatments on the molecular structure, crystalline structure, in vitro digestibility, and physicochemical properties of starches isolated from hydrothermally treated brown rice flour was investigated. Annealed rice starch (ANN) exhibited no significant change in molecular structure, whereas heat-moisture treated rice starch (HMT) showed decreased apparent amylose content, molecular weight of amylopectin, average chain length of amylopectin, and long amylopectin branch chains (DP >=> 37). The relative crystallinity, intensity ratio of 1045 cm(-1)-1015 cm(-1), and gelatinization enthalpy remained unchanged in ANN, but significantly decreased in HMT. In dually modified starches, the HMT-ANN had higher gelatinization temperatures, gelatinization enthalpy, relative crystallinity and ratio of 1045 cm(-1)-1015 cm(-1) than the ANN-HMT. Hydrothermal treatment substantially increased starch digestibility in the granular state, showing increased rapidly digestible starch (RDS) content and decreased resistant starch (RS) content. However, in the gelatinized starches, ANN and HMT showed decreased RDS level and increased slowly digestible starch (SDS) and RS levels. The changes in amounts of RDS, SDS, and RS in ANN, HMT and dually modified starches could be attributed to the alteration of crystalline and molecular structures. (C) 2016 Elsevier Ltd. All rights reserved.</P>
A Design Method for Cascades Consisting of Circular Arc Blades with Constant Thickness
Bian, Tao,Han, Qianpeng,Bohle, Martin Korean Society for Fluid machinery 2017 International journal of fluid machinery and syste Vol.10 No.1
Many axial fans have circular arc blades with constant thickness. It is still a challenging task to calculate their performance, i.e. to predict how large their pressure rise and pressure losses are. For this task a need for cascade data exists. Therefore, the designer needs a method which works quickly for design purposes. In the present contribution a design method for such cascades consisting of circular arc blades with constant thickness is described. It is based on a singularity method which is combined with a CFD-data-based flow loss model. The flow loss model uses CFD-data to predict the total pressure losses. An interpolation method for the CFD-data are applied and described in detail. Data of measurements are used to validate the CFD-data and parameter variations are conducted. The parameter variations include the variation of the camber angle, pitch chord ratio and the Reynolds number. Additionally, flow patterns of two dimensional cascades consisting of circular arc blades with constant thickness are shown.
In Vitro and In Vivo Studies of Topical Delivery System of Gentisic Acid in Hairless Mice
Bian, ShengJie,Zheng, JunMin,Kim, Jung-Sun,Choi, Myeong Jun,Chung, Ho-Kwon,Lee, Chi-Ho,Kim, Dae-Duk 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.3
Gentisic acid is a skin-whitening agent which inhibits the tyrosinase activity, an essential enzyme in the process of biological synthesis of melanin. Since melanin is synthesized in melanocytes located between the viable epidermis and dermis layer, drug amount delivered into the epidermis/dermis layer can provide valuable information for the biological effect of skin-whitening agents. The purpose of this study was to prepare the gentisic acid patches with 2% dodecylamine as enhancer, and to observe the in vitro skin permeation and in vivo skin deposition of gentisic acid. Gentisic acid in Duro-Tak 87-2510 patch formulation permeated across hairless mouse skin at the rate of 40.79㎍/㎠/hr. In vivo study showed that the gentisic acid amount in both the stratum corneum and the viable epidermis/dermis increased with the increase of application time. The amount of gentisic acid in the stratum corneum was higher than that in the epidermis/dermis layer, and was expected to provide a reservoir effect even after removing the patches. Thus, the patch formulation seems to be useful for the topical delivery of ski-whitening agent into the epidermis/dermis layer, the target site.
Structural Mechanisms of the Cooling Rate Effect on the Deformation Behaviors in Metallic Glasses
Bian Zhou,Ming‑fei Li,Fan Xiong,Liang Yang 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5
In this work, the structural mechanisms of the cooling rate effect on the deformation behaviors in metallic glasses (MGs) isstudied, by performing the synchrotron radiation-based experiments coupled with a series of simulations. It is found that aMG prepared at lower cooling rate has the higher yield strength and is more likely to soften itself, resulting in lower plasticity.This is because some atomic-to-cluster level structural factors, such as coordination numbers, atomic packing efficiencies,cluster concentrations and regularities. In addition, a quantitative analysis reveals that higher cooling rate leads to more freevolumes, and significantly affect the evolution of free volumes during the compressive deformation, tuning the formationand the evolution of shear transformation zones, as well as the yield strength and the plasticity.
Minimal flavored U(1)′ for B -meson anomalies
Bian, Ligong,Choi, Soo-Min,Kang, Yoo-Jin,Lee, Hyun Min American Physical Society 2017 Physical Review D Vol.96 No.7
<P>We consider an anomaly free U(1)' model with favorable couplings to heavy flavors in the Standard Model ( SM), as motivated by B- meson anomalies at LHCb. Taking the U(1)' charge to be Q' = y(L mu - L tau) + x(B-3 - L-3), we can explain theB- meson anomalies without invoking extra charged fermions or flavor violation beyond the SM. We showthat there is a viable parameter space with a small x that is compatible with other meson decays, tau lepton, and neutrino experiments as well as theLHCdimuon searches. We briefly discuss the prospects of discovering the Z' gauge boson at the LHC in the proposed model.</P>
Clinical Applicability of Multi-Tumor Marker Protein Chips for Diagnosing Ovarian Cancer
Bian, Jing,Li, Bo,Kou, Xian-Juan,Wang, Xu-Na,Sun, Xiao-Xu,Ming, Liang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19
Purpose: To assess the value of multi-tumor marker protein chips in the diagnosis and treatment of ovarian cancer. Materials and Methods: Twelve tumor markers (CA19-9, NSE, CEA, CA242, CK19, ${\beta}$-HCG, AFP, SCC, c-PSA, CA125, CA724 and CA15-3) were detected by protein biochip in 220 patients with ovarian carcinomas, 205 with benign ovarian tumors and 200 healthy subjects. Results: The positivity rate was obviously higher in ovarian cancer (77.7%), than that in the benign cases (26.3%, p<0.01) and healthy subjects (4.5%, p<0.01). Serum levels of tumor markers were furthermore significantly higher in cases with lymph node metastasis (86.8%) than those without metastasis (44.7%), p<0.01. Conclusions: Multi-tumor marker protein chips provide important assistance in the diagnosis and treatment evaluation in ovarian cancers.