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        THE INCLUSION THEOREMS FOR GENERALIZED VARIABLE EXPONENT GRAND LEBESGUE SPACES

        Aydin, Ismail,Unal, Cihan The Kangwon-Kyungki Mathematical Society 2021 한국수학논문집 Vol.29 No.3

        In this paper, we discuss and investigate the existence of the inclusion L<sup>p(.),𝜃</sup> (𝜇) ⊆ L<sup>q(.),𝜃</sup> (𝜈), where 𝜇 and 𝜈 are two finite measures on (X, Σ). Moreover, we show that the generalized variable exponent grand Lebesgue space L<sup>p(.),𝜃</sup> (Ω) has a potential-type approximate identity, where Ω is a bounded open subset of ℝ<sup>d</sup>.

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        Is Obstructive Sleep Apnea a Risk Factor for Severe COVID-19?

        Zerman Nermin,Aydin Cihan 대한수면학회 2023 sleep medicine research Vol.14 No.2

        Background and Objective Obstructive sleep apnea (OSA) is a breathing disorder during sleep with an obstruction of the upper airway. Previous studies showed OSA as a risk factor for severe COVID-19. It is crucial to determine the risk factors for the severity of COVID-19 infection. We aim to clarify the relationship between COVID-19 severity, and OSA and its degree.Methods Our case-control study included subjects diagnosed with OSA with polysomnography between January 2018 and November 2021, and a control group with a history of COVID-19 infection and without OSA diagnosis. The demographic data, comorbidities, apnea–hypopnea index, and oxygen desaturation index were recorded.Results A total of 217 patients were included in our study. The degree of OSA was a risk factor in the OSA group (p < 0.05); on the other hand, the diagnosis of OSA by itself was not a risk factor. The apnea–hypopnea index and oxygen desaturation index were not related to the severity of COVID-19 infection (p > 0.05). Diabetes mellitus was associated with increased hospitalization in inpatient clinics (p < 0.05) and intensive care unit (ICU) (p < 0.05). Chronic obstructive pulmonary disease was a risk factor for admission to the ICU (p < 0.05).Conclusions Our results showed that moderate-to-severe OSA patients are a vulnerable population to severe COVID-19 infection, although diagnosis of OSA by itself was not a risk factor.

      • KCI등재

        Intravesical Sodium Chondroitin Sulphate to Treat Overactive Bladder: Preliminary Result

        Lokman Irkilata,Mustafa Aydin,Hasan Riza Aydin,Hüseyin Cihan Demirel,Mustafa Kadihasanoglu,Mustafa Kemal Atilla 대한배뇨장애요실금학회 2015 International Neurourology Journal Vol.19 No.2

        Purpose: This study aimed to verify the efficacy and safety of intravesical treatment with sodium chondroitin sulfate (CS) in patients with overactive bladder (OAB) who are refractory to previous antimuscarinic treatment. Methods: This study was performed between June 2012 and January 2015 and included 31 consecutive women (mean age, 42.10±7.34 years) with OAB who had been previously treated with two types of antimuscarinic drugs. The results of gynecologic and cystoscopic examinations were normal, and OAB comorbidity was absent. Treatment with intravesical instillations containing 40 mL CS (0.2%; 2 mg/mL) was administered for 6 weeks; after weekly treatments, monthly treatments were administered. The OAB-validated 8 (OAB-V8) symptom scores, nocturia, frequency, urgency, urge incontinence, and urinary volumes measured by uroflowmetry were evaluated for all the patients. The values obtained before the treatment were statistically compared with those obtained six months after the treatment. Results: The duration of the symptoms was 18.36±6.19 months. A statistically significant improvement of the patients’ conditions was observed in terms of the OAB-V8 symptom scores, nocturia, frequency, urgency, urge incontinence, and urinary volumes measured by uroflowmetry after the treatment. Conclusions: Despite the limitations of this study, the outcomes confirmed that CS therapy is safe and effective for the treatment of OAB.

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