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      저자 : Ayça Uran Şan (검색결과 1 건)
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        Te Efect of Repetitive Transcranial Magnetic Stimulation on Spasticity in Patients with Multiple Sclerosis

        Ayça Uran Şan,Bilge Yılmaz,Serdar Kesikburun 대한신경과학회 2019 Journal of Clinical Neurology Vol.15 No.4

        Background and Purpose Tis randomized controlled study examined the efect of repetitive transcranial magnetic stimulation (rTMS) on spasticity in patients with multiple sclerosis (MS). Methods Tis study included 16 patients with a history of MS and spasticity in the adductor hip muscles according to the Modifed Ashworth Scale (MAS). Te participants were randomized into the active group (n=10) and control group (n=6), in which active rTMS and sham rTMS were applied in 10 sessions, respectively. A physical therapy and rehabilitation program was applied along with rTMS sessions in both groups. Te evaluation parameters were assessed at baseline and then 1 week and 1 month afer applying rTMS. Results Statistical analyses with post-hoc correction revealed statistically signifcant improvements in the active group compared to the control group in the bilateral MAS score, Penn Spasm Frequency Scale score, patient satisfaction, amount of urine leakage, actual health status, perceived health status, energy and fatigue, role limitations due to physical problems, social function, overall quality of life, cognitive functioning, physical health composite score, mental health composite score, and total score on the Multiple Sclerosis Quality of Life-54 (MSQOL-54) (p< 0.05). Statistically signifcant changes were detected in the MSQOL-54 social function and physical health composite scores of patients in the control group (p<0.05). Conclusions Active rTMS combined with a physical therapy program reduced spasticity in MS patients compared to the control group that received only physical therapy. Further comprehensive and more advanced studies are needed to confrm the present fndings.

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