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Antimicrobial Activity of New 4,6-Disubstituted Pyrimidine, Pyrazoline, and Pyran Derivatives
Mahmoud M. M. Ramiz,Wael A. El-Sayed,Asmaa I. El-Tantawy,Adel A. H. Abdel-Rahman 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.5
A number of new 2,6-didisubstituted pyrimidine, pyrazoline, and pyran derivatives were synthesized starting from their chalcone derivative. The synthesized compounds displayed different degrees of antimicrobial activity against Bscillus subtilis (Gram-positive), Pseudomonas aeruginosa (Gram-negative), and Streptomyces species (Actinomycetes).