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Simone Scarcella,Daniele Castellani,Vineet Gauhar,Jeremy Yuen-Chun Teoh,Carlo Giulioni,Pietro Piazza,Carlo Andrea Bravi,Ruben De Groote,Geert De Naeyer,Stefano Puliatti,Andrea Benedetto Galosi,Alexand 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.6
Purpose: To review safety and efficacy of robotic-assisted simple prostatectomy (RASP) compared to open simple prostatectomy (OP). Materials and Methods: A comprehensive literature search was performed to assess the differences in perioperative course and functional outcomes in patients with benign prostatic hyperplasia and surgical indication. The incidences of complications were pooled using the Cochran–Mantel–Haenszel Method and expressed as odds ratio (OR), 95% confidence interval (CI), and p-values. Perioperative course and functional outcomes were pooled using the inverse variance of the mean difference (MD), 95% CI, and p-values. Analyses were two-tailed and the significance was set at p<0.05. Results: Eight studies were accepted. Meta-analysis showed significantly longer surgical time (MD, 43.72; 95% CI, 30.57–56.88; p<0.00001) with a significantly lower estimated blood loss (MD, -563.20; 95% CI, −739.95 to −386.46; p<0.00001) and shorter postoperative stay (MD, −2.85; 95% CI, −3.72 to −1.99; p<0.00001) in RASP. Catheterization time did not differ (MD, 0.65; 95% CI, −2.17 to 3.48; p=0.65). The risk of blood transfusion was significantly higher in OP (OR, 0.23; 95% CI, 0.17–0.33; p<0.00001). The risk of recatheterization (OR, 1.96; 95% CI, 0.32–11.93; p=0.47), postoperative urinary infections (OR, 0.89; 95% CI, 0.23–3.51; p=0.87) and 30-day readmission rate (OR, 0.96; 95% CI, 0.61–1.51; p=0.86) did not differ. At 3-month follow-up, functional outcomes were similar. Conclusions: RASP demonstrated a better perioperative outcome and equal early functional outcomes as compared to OP. These findings should be balanced against the longer operative time and higher cost of robotic surgery.
Carlo Giulioni,Giacomo Maria Pirola,Martina Maggi,Lucia Pitoni,Demetra Fuligni,Mattia Beltrami,Vanessa Palantrani,Virgilio De Stefano,Valentina Maurizi,Daniele Castellani,Andrea Benedetto Galosi 대한배뇨장애요실금학회 2024 International Neurourology Journal Vol.28 No.1
To assess the effectiveness and safety of various techniques of pudendal nerve neurolysis (PNN) in patients with pudendal nerve entrapment (PNE). A comprehensive literature search was conducted on May 20th, 2023, using Scopus, PubMed, and Embase databases. Only studies in English involving adults were accepted, while meeting abstracts and preclinical studies were excluded. A total of 34 papers were included. Transperineal PNN emerged as a promising technique, demonstrating significant potential in alleviating pain, restoring erectile function in males, and improving the resolution of urinary stress incontinence in females. Furthermore, the bilateral approach consistently yielded positive outcomes in addressing urinary symptoms. The transgluteal technique appeared particularly suitable for cases of posterior PNE, situated between the sacrospinous ligament and the lesser sciatic foramen. A progressive amelioration of painful symptoms was observed during follow-up. Minimally invasive PNN is evolving and enables decompression along the entire proximal tract up to the Alcock canal, minimizing the risk of comorbidities. In addition to reducing pudendal neuralgia, robot-assisted and laparoscopic approaches determined a reduction in lower urinary tract symptoms and an improvement in erectile function, though further studies are required to corroborate these findings. PNN emerges as an effective treatment for PNE with minimal morbidity. Therefore, PNN should be tailored according to the site of PNE to enhance functional outcomes and improve patient quality of life.