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      • Cancer Awareness among University Students in Turkey

        Kurtuncu, Meltem,Akhan, Latife Utas,Celik, Sevecen,Alkan, Isin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

        Background: One of the most important reasons for the high mortality rates of cancer is the low level of awareness, which can lead to a late diagnosis and treatments starting too late. Therefore, it is necessary for individuals, especially at younger age, to gain awareness and integrate taking the necessary precautions into their lifestyle in order to prevent cancer and ensure early diagnosis. The aim of this study was to assess the levels of awareness of factors for major cancers among students studying in two different campuses of a university in the Western Black Sea Region. Materials and Methods: This descriptive/cross-sectional study was performed between January-March 2014. Students studying in the 2013-2014 academic year in a university in the Western Black Sea Region in two separate campuses were the subjects. Results: The mean age was $21.01{\pm}3.63$. While female students (51.2%) were the majority in the health sciences campus (74.8%), male students (48.8%) were the majority in the social sciences campus (76.5%). Some 9.6% of the students from the health sciences campus and 12.4% of the students from the social sciences campus thought that cancer was communicable, while most of the students from both campuses knew that smoking caused cancer. It can also be seen that the rate of answering questions regarding cancer correctly was higher among students studying in the health sciences campus. Conclusions: It was determined that students who do not study at the health sciences campus have insufficient information on cancer, cancer symptoms, and the possibility of breast cancer in males and approximately half of them regarded obesity as a risk factor for cancer.

      • Synthesis of a Watt II six-bar linkage in the design of a hand rehabilitation robot

        Gezgin, E.,Chang, P.H.,Akhan, A.F. Pergamon Press 2016 Mechanism and machine theory Vol.104 No.-

        As a result of neurological disorders such as stroke, brain and spinal cord injuries, disability in body regions might occur. In case of similar situations, rapid therapeutic training in early stages has chance to prevent permanent disability by retraining motor movements. In regular treatments, therapists help to carry out regular exercises to train motor movements of the disabled region. However, continuous increase in cases, tough working conditions, dependability on expertise and human body limitations make the procedures cumbersome and ineffective. Incorporating robots into therapeutic training not only allows executing treatments in a delicate repeatability but also opens new possibilities in terms of exercise types and speeds. In the light of recent developments in robotic rehabilitation this paper presents the design of a hand rehabilitation robot for human four fingers that solely targets hand disabilities by utilizing real grasping motion data of the forefinger into kinematic synthesis of Watt II six-bar linkage. During the design geometrical synthesis was used for the first loop in order to attain continuous input rotation and the body-guidance synthesis was used for the second loop for the end effector to follow the desired trajectory in desired orientations.

      • Poster Session : PS 0098 ; Cardiology : R Wave Amplitude of Avl Derivation Seems to be Important in Predicting Arterial Stiffness Parameters

        ( Hakan Sarlak ),( Fatih Bulucu ),( Erol Arslan ),( Seref Demirbas ),( Muharrem Akhan ),( Sait Demirkol ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

        Background: Studies have shown that arterial stiffness is an independent predictor of cardiovascular diseases. Left ventricular hypertrophy (LVH) is an independent risk factor for early death. It is caused by malignant ventricular arrhythmias due to ventricular hypertrophy. In this study we aimed to investigate the relationships between arterial stiffness parameters and electrocardiographic criteria for LVH. Methods: A total of 59 subjects (30 females, 29 males) were included into the study. The subjects were the patients having arterial stiffness and electrocardiographic measurements applied in the internal medicine out-patient clinics for their chronic diseases or based upon their complaints. Results: The pulse wave velocity (PWV) was signifi cantly associated with Sokolow-Lyon ‘II’ (r=0.269; p=0.041) and the central aortic pressure (CAP) was signifi cantly associated with Sokolow-Lyon ‘II’ and Romhilt-Estes Score (r=0.303; p=0.021 and r=0.275; p=0.037, respectively) in whole group. The augmentation index of aortic (AIXao) was signifi cantly associated with Sokolow-Lyon ‘II’ (r=0.381; p=0.042) in men. The CAP was signifi cantly associated with Sokolow-Lyon ‘II’, Cornell Product and Romhilt-Estes Score (r=0.524; p=0.004, r=0.402; p=0.031 and r=0.444; p=0.016, respectively) in women. Conclusions: These data suggest that some arterial stiffness parameters may be predicted by using R wave amplitude of aVL derivation. Although our small scale preliminary investigation confers some clues for this approach, it is obvious that large scale and more detailed investigations are needed.

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        Long-term results of radiofrequency and microwave ablation of colorectal cancer liver metastasis

        Ahmet Gürkan Erdemir,Sevilay Karahan,Emre Ünal,Türkmen Turan Çiftçi,Devrim Akıncı,Şuayib Yalçın,Okan Akhan 소화기인터벤션의학회 2023 International journal of gastrointestinal interven Vol.12 No.3

        Background: Radiofrequency ablation (RFA) or microwave ablation (MWA) is effective for colorectal cancer liver metastases. We aimed to investigate the impact of different variables on survival. Methods: Sixty-four patients (142 lesions) who underwent thermoablation between January 2007 and January 2019 were retrospectively analyzed. The overall survival (OS) and liver progression-free survival (Li-PFS) were compared using Kaplan-Meier analysis. Univariable and multivariable Cox-regression were done to identify prognostic factors. Results: No significant difference was found between median OS (59.39 months) and Li-PFS (41.22 months) of patients who received MWA (n = 33); and median OS (61.00 months) and Li-PFS (53.43 months) of patients who received RFA (n = 31) (OS: P = 0.697; Li-PFS: P = 0.122). The median OS and Li-PFS were significantly decreased with lung metastases and K-ras mutations (P < 0.001). There was no correlation between prior systemic chemotherapy (n = 25) and both outcome parameters (OS: P = 0.613; Li-PFS: P = 0.665). No significant difference was observed in patients with lesions less than 30 mm diameter (n = 44) whether they received prior systemic chemotherapy (n = 17) or not (n = 27) (OS: P = 0.27; Li-PFS: P = 0.42). Similarly, in patients with a lesion of 3–5 cm diameter (n = 20; eight of them had prior chemotherapy), there was no correlation for both outcomes (OS: P = 0.069; Li-PFS: P = 0.71). The most important prognostic factor was concomitant lung metastases (hazard ratio = 3.689, P = 0.002). Conclusion: Concomitant lung metastasis and mutant K-ras were associated with shorter survival. Survival did not differ significantly regarding thermoablation technique or prior systemic chemotherapy. However, in the patient group with lung metastases, curative treatments had better survival than patients who received chemotherapy only. Additional therapeutic options should be considered in patients with concomitant lung metastasis.

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