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- 저자 : Abdul Rehman Khalid (검색결과 2 건)
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Abdul Rehman Khalid,Ali Athar,Hee-Cheol Kim 한국정보통신학회 2023 한국정보통신학회 종합학술대회 논문집 Vol.27 No.1
This paper examines the problem of counterfeit medicines and illicit drugs, which represent serious threats to public health and safety across the world. Counterfeit medicines are forgeries that may include hazardous substances, whereas illicit drugs are prohibited to manufacture, distribute, or consumption. We synthesize the existing research on the application of artificial intelligence (AI) algorithms for identifying and detecting counterfeit healthcare products and illegal drug transactions on social media in this review paper. We examine the use of artificial intelligence techniques on social media to detect suspicious activity connected to counterfeit healthcare products and illicit drugs. Our findings suggest that artificial intelligence algorithms have a high potential for identifying and preventing the sale of counterfeit healthcare products and illicit drugs on social media.
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Carbonic anhydrase influences asymmetric sodium and acetate transport across omasum of sheep
Rabbani, Imtiaz,Rehman, Habib,Martens, Holger,Majeed, Khalid Abdul,Yousaf, Muhammad Shahbaz,Rehman, Zia Ur Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.5
Objective: Omasum is an important site for the absorption of short chain fatty acids. The major route for the transport of acetate is via sodium hydrogen exchanger (NHE). However, a discrepancy in the symmetry of sodium and acetate transport has been previously reported, the mechanism of which is unclear. In this study, we investigated the possible role of carbonic anhydrase (CA) for this asymmetry. Methods: Omasal tissues were isolated from healthy sheep (N = 3) and divided into four groups; pH 7.4 and 6.4 alone and in combination with Ethoxzolamide. Electrophysiological measurements were made using Ussing chamber and the electrical measurements were made using computer controlled voltage clamp apparatus. Effect(s) of CA inhibitor on acetate and sodium transport flux rate of Na22 and 14C-acetate was measured in three different flux time periods. Data were presented as mean±standard deviation and level of significance was ascertained at p≤0.05. Results: Mucosal to serosal flux of Na (JmsNa) was greater than mucosal to serosal flux of acetate (JmsAc) when the pH was decreased from 7.4 to 6.4. However, the addition of CA inhibitor almost completely abolished this discrepancy (JmsNa ≈ JmsAc). Conclusion: The results of the present study suggest that the additional protons required to drive the NHE were provided by the CA enzyme in the isolated omasal epithelium. The findings of this study also suggest that the functions of CA may be exploited for better absorption in omasum.
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