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Dynamic interaction analysis of a LIM train and elevated bridge system
H. Xia,W. W. Guo,C. Y. Xia,Y.-L. Pi,M. A. Bradford 대한기계학회 2009 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.23 No.12
A three-dimensional dynamic interaction model is developed for a LIM (linear induction motor) train and elevated bridge system, which is composed of a LIM-driven vehicle submodel and a finite element bridge submodel. Each LIM vehicle is modeled by a 27 degrees-of-freedom dynamic system. The expressions for the electromagnetic force between the linear motor and the reaction plate are derived, and the force model is established. By applying a modal superposition technique to the bridge submodel and using the measured track irregularities as the self-excitations of the train-bridge system, the equations of motion are established for analyzing the dynamic responses of the LIM vehicle and the elevated bridge. The proposed framework is applied to a 3-span elevated bridge with 29.9 m simply-supported girders. The full histories of the LIM train traversing the bridge are simulated, from which the dynamic responses of the LIM vehicle and elevated bridge system are obtained. The proposed method may help to find a way to assess the dynamic properties of elevated bridges and the running safety of a LIM train with reasonable computational effort.
Xia, L.,Idhayadhulla, A.,Lee, Y.R.,Kim, S.H.,Wee, Y.J. Korean Society of Industrial and Engineering Chemi 2015 Journal of industrial and engineering chemistry Vol.22 No.-
Diverse 3,5,6,7-tetrahydrobenzofuran-4-one derivatives (3a-3n) were synthesized in high yields by ruthenium complex or rhodium complex catalyzed [3+2] cycloaddition. The antibacterial activities of these 3,5,6,7-tetrahydrobenzofuran-4-ones were evaluated against Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter aerogenes) and Gram-positive bacteria (Bacillus cereus and Staphylococcus aureus). In particular, compound 3b showed the highest antibacterial activity against P. aeruginosa and S. aureus (both MICs: 2μg/mL). Compound 3l, which has the 2H-pyrano[2,3-b]benzofuran skeleton, exhibited excellent inhibitory activity against B. cereus (MIC: 0.5μg/mL) as compared with ciprofloxacin (MIC: 2μg/mL) and ampicillin (MIC: 1μg/mL).
Observation of the topological surface state in the nonsymmorphic topological insulator KHgSb
Liang, A. J.,Jiang, J.,Wang, M. X.,Sun, Y.,Kumar, N.,Shekhar, C.,Chen, C.,Peng, H.,Wang, C. W.,Xu, X.,Yang, H. F.,Cui, S. T.,Hong, G. H.,Xia, Y.-Y.,Mo, S.-K.,Gao, Q.,Zhou, X. J.,Yang, L. X.,Felser, C. American Physical Society 2017 Physical review. B Vol.96 No.16
<P>Topological insulators represent unusual topological quantum states, typically with gapped bulk band structure but gapless surface Dirac fermions protected by time-reversal symmetry. Recently, a distinct kind of topological insulator resulting from nonsymmorphic crystalline symmetry was proposed in the KHgX (X = As, Sb, Bi) compounds. Unlike regular topological crystalline insulators, the nonsymmorphic glide-reflection symmetry in KHgX guarantees the appearance of an exotic surface fermion with hourglass shape dispersion (where two pairs of branches switch their partners) residing on its (010) side surface, contrasting to the usual two-dimensional Dirac fermion form. Here, by using high-resolution angle-resolved photoemission spectroscopy, we systematically investigate the electronic structures of KHgSb on both (001) and (010) surfaces and reveal the unique in-gap surface states on the (010) surface with delicate dispersion consistent with the 'hourglass Fermion' recently proposed. Our experiment strongly supports that KHgSb is a nonsymmorphic topological crystalline insulator with hourglass fermions, which serves as an important step to the discovery of unique topological quantum materials and exotic fermions protected by nonsymmorphic crystalline symmetry.</P>
Synthesis of novel and diverse mollugin analogues and their antibacterial and antioxidant activities
Idhayadhulla, A.,Xia, L.,Lee, Y.R.,Kim, S.H.,Wee, Y.J.,Lee, C.S. Academic Press ; Academic Press 2014 Bioorganic chemistry Vol.52 No.-
Novel and diverse mollugin analogues (1-12) were synthesized using PhB(OH)<SUB>2</SUB>/AcOH-mediated electrocyclization reaction as a key step. The newly synthesized compounds were screened for antioxidant and antibacterial activities. Compounds 1, 2, 5, 6, 8, and 10-12 showed high antioxidant activities in DPPH inhibition (IC<SUB>50</SUB>=0.52-1.11μM) compared with BHT (IC<SUB>50</SUB>=9.67μM). Compounds 3 exhibited potent antibacterial activity against Staphylococcus aureus (KCTC-1916) bacterial strain at 100μg/mL. Structures of newly synthesized compounds were confirmed by IR, <SUP>1</SUP>H NMR, <SUP>13</SUP>C NMR data and high-resolution mass spectrometry.
Bioluminescent nanosensors for protease detection based upon gold nanoparticle–luciferase conjugates
Kim, Young-Pil,Daniel, Weston L.,Xia, Zuyong,Xie, Hexin,Mirkin, Chad A.,Rao, Jianghong Royal Society of Chemistry 2010 Chemical communications Vol.46 No.1
<P>This communication reports the use of click chemistry to site-specifically conjugate bioluminescent <I>Renilla</I> luciferase proteins to gold nanoparticles (Au NPs) for sensing protease activity. The bioluminescent emission from luciferase was efficiently quenched by Au NPs, but significantly recovered after the proteolytic cleavage.</P> <P>Graphic Abstract</P><P>This communication reports the first demonstration of quenching of bioluminescent emission from luciferase by gold nanoparticles, and the design of a bioluminescent gold nanosensor for sensing protease activity. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b915612g'> </P>