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        Factors associated with the survival of colorectal cancer in Mexico

        ( Carlos Quezada-gutiérrez ),( María Teresa Álvarez-bañuelos ),( Jaime Morales-romero ),( Clara Luz Sampieri ),( Raúl Enrique Guzmán-garcía ),( Evangelina Montes-villaseñor ) 대한장연구학회 2020 Intestinal Research Vol.18 No.3

        Background/Aims: Colorectal cancer (CRC) is a public health problem. In Mexico, there have been no recent studies conducted on survival in terms of this pathology or on the influence of prognostic factors. The study aims to determine the probability of survival in patients with CRC presence of low levels of schooling and a rural population, adjusted for clinical stage and type of treatment. Methods: A retrospective study was conducted in a cohort of 305 patients with CRC treated at State Cancer Center, located in Veracruz-Mexico; the follow-up period of 60 months (2012-2016). The survival probability was calculated using the Kaplan-Meier estimator and the log-rank test with 95% confidence intervals (CIs). Prognostic factors were determined using hazard ratio (HR) multivariate Cox regression analysis. Results: Overall survival was 40% at 60 months. Subjects in the age group ≥65 years had a low survival rate of 28% (P=0.026) and an advanced clinical stage of 22% (P<0.001). Of the patients with bone metastasis, none survived longer than 5 years (P=0.008). With respect to the unfavorable prognostic factors identified in the multivariate analysis, a decreased level of schooling was associated with an HR of 7.6 (95% CI, 1.1-54.7), advanced clinical stage was associated with an HR of 2.1 (95% CI, 1.2-4.0), and the presence of metastasis had an HR of 1.8 (95% CI, 1.1-2.9). Conclusions: Poor prognostic factors include an advanced clinical stage, the presence of metastasis and a low level of schooling. These findings confirm the importance of screening for early diagnosis, diminishing the barriers to accessing treatment and prospectively monitoring the population. (Intest Res 2020;18:315-324)

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        Photo-catalysis of phenol derivatives with Fe2O3 nanoparticles dispersed on SBA-15

        E. Montiel-Palacios,A. K. Medina-Mendoza,A. Sampieri,C. Angeles-Chávez,I. Hernández-Pérez,R. Suarez-Parra 한양대학교 세라믹연구소 2009 Journal of Ceramic Processing Research Vol.10 No.4

        Highly ordered hexagonal (p6mm) mesoporous silica SBA-15 was synthesized through a hydrothermal treatment under acidic conditions. Fe2O3/SBA-15 catalysts were prepared by impregnation of SBA-15 media with iron(III) acetylacetonate, iron(III) chloride or iron(II) sulfate solutions. X-ray Diffraction (XRD), X-ray fluorescence (XRF), high angle annular dark field scanning transmission electron microscopy (HAADF-STEM), energy dispersive X-ray (EDX) spectroscopy and nitrogen physisorption characterization were carried out for SBA-15 and Fe2O3/SBA-15 materials. After impregnation and calcination at 823 K, the iron oxide dispersion in SBA-15 was analyzed by STEM and EDX. FeCl3 provides the highest amount of Fe loading in mesoporous SBA-15. The photocatalytic properties of Fe2O3/SBA-15 samples at pH = 3 and pH = 6 were evaluated in catechol and hydroquinone photodecomposition by inducing visible radiation. The conversion of catechol and hydroquinone, at pH = 3 and pH = 6 with iron(III) acetylacetonate and FeCl3 as the precursor of iron oxide nanoparticles, were measured by UV-Vis spectroscopy, chemical oxygen demand (COD) and total organic carbon (TOC) analysis. Highly ordered hexagonal (p6mm) mesoporous silica SBA-15 was synthesized through a hydrothermal treatment under acidic conditions. Fe2O3/SBA-15 catalysts were prepared by impregnation of SBA-15 media with iron(III) acetylacetonate, iron(III) chloride or iron(II) sulfate solutions. X-ray Diffraction (XRD), X-ray fluorescence (XRF), high angle annular dark field scanning transmission electron microscopy (HAADF-STEM), energy dispersive X-ray (EDX) spectroscopy and nitrogen physisorption characterization were carried out for SBA-15 and Fe2O3/SBA-15 materials. After impregnation and calcination at 823 K, the iron oxide dispersion in SBA-15 was analyzed by STEM and EDX. FeCl3 provides the highest amount of Fe loading in mesoporous SBA-15. The photocatalytic properties of Fe2O3/SBA-15 samples at pH = 3 and pH = 6 were evaluated in catechol and hydroquinone photodecomposition by inducing visible radiation. The conversion of catechol and hydroquinone, at pH = 3 and pH = 6 with iron(III) acetylacetonate and FeCl3 as the precursor of iron oxide nanoparticles, were measured by UV-Vis spectroscopy, chemical oxygen demand (COD) and total organic carbon (TOC) analysis.

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