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A ´ngel L. A ´ lvarez,Santiago Melo´n,Kevin P. Dalton,Ine´s Nicieza,Annele Roque,Bele´n Sua´rez,Francisco Parra 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.6
The anti–herpes simplex virus type 1 and anti–herpes simplex virus type 2 effects of apple pomace, a byproduct from the cider-processing industry, were investigated. The mechanisms of antiviral action were assessed using a battery of experiments targeting sequential steps in the viral replication cycle. The anti-herpetic mechanisms of apple pomaces included the inhibition of virus attachment to the cell surface and the arrest of virus entry and uncoating. Quercitrin and procyanidin B2 were found to play a crucial role in the antiviral activity.