http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 황현철 ( Hyun-chul Whang ) (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
신장 ; 다발성 골수종에서 신부전 발생의 위험인자 및 신기능 회복 예측인자
황현철 ( Hyun Chul Whang ),고은실 ( Eun Sil Koh ),김정관 ( Jeong Gwan Kim ),정성진 ( Sung Jin Chung ),신석준 ( Seok Joon Shin ),박철휘 ( Cheol Whee Park ),장윤식 ( Yoon Sik Chang ) 대한내과학회 2014 대한내과학회지 Vol.86 No.2
목적: 신부전은 다발성 골수종에서 종종 발생하며 나쁜 예후를 보인다. 아시아의 다발성 골수종의 발생빈도와 특징은 서양과는 다른 것으로 알려져 있다. 이 연구의 목적은 다발성 골수종 환자들에서 신부전 발생의 위험인자 및 치료 후 신기능 회복 인자를 찾고자 하였다. 방법: 2005년부터 2008년까지 처음 다발성 골수종을 진단 받은 환자를 대상으로 하여 신부전의 발생과 관련된 인자를 조사하였고, 12주간의 치료 후에 신부전의 회복과 관련된 인자를 찾았다. 결과: 진단 당시 221명의 환자 중 86명(39%)에서 신부전이 발생하였다. 이변량 로지스틱 회기 분석에서 낮은 헤모글로빈(OR = 0.813, p = 0.02), 높은 베타-2 마이크로글로불린(OR = 1.006, p < 0.01), ACEi (OR = 2.783, p = 0.04) 사용이 신부전 발생의 독립적인 위험인자로 나타났다. 12주간의 치료 후, 86명 중에서 25 (29%)명의 신기능이 회복되었다. 항암치료에 반응을 보인 경우(OR = 6.044, p < 0.01)와 높은 eGFR (OR = 1.084, p < 0.01)이 회복과 연관된 인자로 나타 났다. 결론: 헤모글로빈 수치, 베타-2 마이크로글로불린, ACEi의 사용이 한국 다발성 골수종 환자에 있어 신부전 발생의 독립적인 위험인자이며 항암 치료에 반응여부와 진단 시의 eGFR이 신기능 회복의 예측인자이다. Background/Aims: Multiple myeloma (MM) is frequently accompanied by renal insufficiency, which has been regarded as a poor prognostic factor for MM. It is known that the incidence and characteristics of MM in Asia differ from those in Western countries. The aim of this study was to evaluate risk factors for renal impairment and to investigate reversible factors for renal failure in patients with MM. Methods: Patients newly diagnosed with MM from 2005 to 2008 were included. We investigated factors associated with renal insufficiency and those related to recovery from renal dysfunction after 12 weeks of treatment of MM. Results: Renal failure was recognized in 86 (39%) of 221 patients at diagnosis. In the binary logistic regression analysis, low hemoglobin (odds ratio [OR], 0.813; p = 0.02), high β2microglobulin (OR, 1.006; p < 0.01), and use of angiotensin-converting enzyme inhibitors (ACEi) (OR, 2.783; p < 0.04) at initial presentation were independent risk factors for renal failure in patients with multiple myeloma. After 12 weeks of treatment, 25 of 86 (29%) patients with renal failure had recovered renal function. Good response to chemotherapy (OR, 6.044; p < 0.01) and higher eGFR (OR, 1.084; p < 0.01) were associated with renal function recovery. Conclusions: Levels of hemoglobin and β2microglobulin, and use of ACEi were independent risk factors for the development of renal failure in MM patients. The response to chemotherapy and eGFR at diagnosis significantly influenced recovery of renal function. (Korean J Med 2014;86:190-197)
-
한국군에서의 한타박스<sup>®</sup> (HFRS국내백신)의 효용성에 대한 연구
손민정 ( Min-jeong Son ),황현철 ( Hyun-chul Whang ),양병윤 ( Byeon-yun Yang ),최강원 ( Kang-won Choe ),박영준 ( Young-joon Park ),황세민 ( Se-min Hwang ),채동완 ( Dong-wan Chae ) 국군의무사령부 2011 대한군진의학학술지 Vol.42 No.1
Introduction: Hemorrhagic fever with renal syndrome (HFRS), although its incidence is decreasing, reveals severe renal clinical course and high mortality. Military croups have many outdoor activities, so soldiers cannot avoid to exposure of Hantan virus in epidemic area in Korea. Therefore, soldiers in epidemic area were scheculed to vaccinate HantavaxⓇ which is intoxicated vaccine. this study aims that HantavaxⓇ can influence with the clinical course of HFRS. Methods: Twenty nine male patients ,who were diagnosed HFRS in the Armed Forces Capital Hospital, were retrospectively enrolled from March 2009 to July 2010. Patients have positive results in Hantan virus antibody using with rapid chromatography test and they have no history of vaccination within three month recently. Nephrology specialist diagnosed the HFRS in patient and enrolled them in study group. All patients were confirmed the vaccination history which is based on public record of his croup, not his memory's. Researchers could check patient's precise vaccination history, the day and the times. We classified patients by non-vaccination patients (group 1) and vaccination patient (group 2) and investigated clinical course of both groups. Results: Eleven patients (37.9%) had been vaccinated previously and eighteen patient had not had vaccination. None of study patients was died. six patients of group 1 must have been dialysis treatment during acute status and none of group 2 were not dialysis treatment. Eleven patients of group 1 experienced oliguria, but only one patient of group 2 have oliguric phase. These clinical course shows stastically different from group 1 and group 2(p=0.032, p=0.011). These results are announced that vaccination might have protective effect against the HFRS. Admission day, titer of antibody, hematologic and chemical test were not different among two groups. Conclusion: Vaccination group of HantavaxⓇ in patients had better clinical course than non-vaccination group. Additional study should be needed for evaluating of renal protective effect of HantavaxⓇ.
-
증례 : 신장; 말기신부전 환자에서 Candida famata에 의해 발생한 심내막염
김정관 ( Jeong Gwan Kim ),황현철 ( Hyun Chul Whang ),장지연 ( Ji Yeon Jang ),하성은 ( Seong Eun Ha ),김동휘 ( Dong Hwi Kim ),최범순 ( Bum Soon Choi ) 대한내과학회 2014 대한내과학회지 Vol.86 No.3
Infective endocarditis is rare in end-stage renal disease (ESRD) patients, who have a poorer prognosis than the general population. Candida endocarditis is rare and has a poor prognosis among causes of infective endocarditis. A 45-year-old male was admitted with sepsis combined with a hematoma on his right back. Candida famata was cultured in his blood. We treated him with antifungal agents. Echocardiography was performed to identify vegetations and diagnose endocarditis. In this case, surgical therapy was impossible because the patient`s condition had deteriorated. We also administered antibiotics because methicillin-resistant Staphylococcus aureus was cultured from his sputum and a perianal abscess. The symptoms did not improve despite the ongoing treatment. Metabolic acidosis, hypotension, and a decreased state of consciousness developed and he died. We report a rare case of Candida endocarditis in an ESRD patient on hemodialysis.
KCI
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
