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RISS 인기검색어
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- 저자 : 홍영범(YJ Hong) (검색결과 2 건)
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홍영범(YJ Hong),양재홍(JS Yang),정순오(SO Chung),곽현모(HM Kwak) 대한산부인과학회 1976 Obstetrics & Gynecology Science Vol.19 No.9
저자들은 1974년 1월부터 1975년 8월말까지 1년 8개월간 연세대학교 의과대학 부속 세브란 스병원에 입원하여 가료를 받았던 환자와 외래환자 중에서 유전적 질환이 의심되는 81예에 대하여 염색체 검사를 실시한 결과 39예의 이상을 얻었다. 그중 Down`s syndrome 13예 Turner`s syndrom 4예 Kleinefelter`s syndrome 2예, sex anomaly 가 19예로 나타났으며 전체 적으로 나타난 핵형의 종류는 다음과 같다. 1. Down`s syndrome은 primary 21 trisomy 와 mosaic type의 2가지가 보여졌다. 2. Turner`s syndrome은 45, X, 46, XX/45, X and 44, X, G/45, X의 3가지 핵형이 있었다. 3. Kleinefelter`s syndrome에서는 47, XXY 와 48, XXYY가 보여졌다. 4. Sex anomaly에는 XY female 와 XXmale 등이 보였다. The numerical and structural aberration of chromosomes were analysed from 81 patients who had been doubted as genetic disease in the genetics laboratory, Yonsei University Medical Center from Jan. 1. 1974 to Aug 31. 1975. Out of the 81 patients 39 had the abnormal karyotypes. 13 cases of Down`s syndrome, 4 cases of Turner`s syndrom , 2 cases of Kleinefelter`s syndrome and 19 cases of sex anomaly were found. All kinds of karyotypes observed were ; 1. Down`s syndrome ; primary 21 trisomy type and mosaic type 2. Turner`s syndrome ; 45, X, 46, XX/45, X and 44, X, G/45, X 3. Kleinefelter`s syndrome ; 47, XXY and 48, XXYY 4. Sex anomaly ; XY female and XXmale etc.
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Prostaglandin F2a의 양막외주입에 의한 중기임신중절
정순오(SO Chung),홍영범(YJ Hong),곽현모(HM Kwak) 대한산부인과학회 1976 Obstetrics & Gynecology Science Vol.19 No.10
Prostagladin F2a was injected extra-amniotically through foley catheter in 26 patients between 15 and 31 weeks gestation in the dosage schedule. Mid-trimester abortion was successfully induced in 26 patients by administration of extra-amniotic PgF2a The mean abortion time for the successful induction was 19.65 hrs. Abortion was successfully induced in 77% of patients within 24 hrs and in 100% within 48 hrs. Multiparous patients aborted somewhat faster than nulliparous patients, but the difference was not sighnificant . Among the 26 successful inductions 20 patients aborted in 24 hrs. the most frequently encountered side effect of extra-amniotic PgF2a administration was a gastriontestinal disturbances-nausea, vomitting and diarrhea. A temperature elevation was also common, which returned to normal within a few hours of last dose of the drug. These side effects were in general well tolerated by the patients and never required therapy or termination. In a single patients surgical intervention was required to remove the placenta. In one patients the placenta was removed by sponge forceps and in one patients the placenta was removed mannually . There was an estimated blood loss exceeding 250ml in one patients but transfusion was not required. Indication of extraamniotic PgF2a administration was intrauterine fetal death in 8 patients and psychosocial problem in 8 patients. the mean pitocin augmentation time for the successful induction was 3.78hours. Multiparous patients aborted somewhat faster than nulliparous patients in pitocin augmentation time but the difference was not sighnificantly. The mean total dosage of PgF2a was 5529ug. The mid-trimester abortion with extra-amniotic administration of PgF2a appears to offer a valid alternative to the presently available techniques, with a rapid abortion time high success rate, low incidence of side effects and complications.
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