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- 저자 : 함정희 ( Ham Jeong Hui ) (검색결과 3 건)
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소아, 청소년 아토피 피부염에서의 DPCP 면역요법의 임상적 치료효과
방숙현 ( Bang Sug Hyeon ),최유원 ( Choe Yu Won ),함정희 ( Ham Jeong Hui ),황규광 ( Hwang Gyu Gwang ) 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.1
N/A Background: Atopic dermatitis is the most common chronic skin disease in childhood. Severe atopic dermatitis may require use of topical or systemic corticosteroids. These treatments are prone to several adverse side effects. This paper highlights the impressive effect of diphenylcycloprope-none(DPCP) sensitization in the some cases of childhood and adolescent atopic dermatitis. Objective: The purpose of this study was to examine the effect of DPCP in treating severe atopic dermatitis of children and adolescents. Methods: Twenty eight patients, who had moderate to severe atopic dermatitis, were recruited in the treatment of DPCP weekly for 10 weeks and followed up for another 4 weeks. Severity of atopic dermatitis was measured using SCORAD index. Results: Sixteen of 28 patients had finished the treatment courses. After 10 weeks of therapy with DPCP, the patient`s symptoms were improved and the mean SCORAD index was significantly reduced from 48.9±17.8 to 18.0±9.1 (p<0.01). During the follow-up period, patients could be managed by topical steroid and oral antihistamine and flare-up was no observed. Conclusion: According to our study, DPCP can be an effective, safe and well-tolerated therapy for moderate to severe atopic derm atitis in children and adolescents. We suggest that DPCP may be effective in the treatment of moderate to severe atopic dermatitis of children and adolescents without serious complications. (Korean J Dermatol 2004;42(1):29-36)
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김지숙 ( Kim Ji Sug ),김명화 ( Kim Myeong Hwa ),최혜영 ( Choe Hye Yeong ),함정희 ( Ham Jeong Hui ),고영훈 ( Go Yeong Hun ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.8
N/A Background : In Korea, the prevalence of leprosy and the number of new indigenous cases has fallen. With this reason, the diagnosis of leprosy is not as easy as in the past and it became more dependent of the histopathologic features by skin biopsy. Object : The aim of this study was to document and analyze the clinical and histopathological features of leprosy in Korea. Methods : We carried out the clinical and histopathological studies on 90 leprosy patients who visited the Institute of Leprosy Control during the period from Jan. 1998 to Aug. 2002. Results : The results obtained were as follows. 1. Elongated granulomas which are frequently observed in the leprosy lesions, was not present in the 3 cases(18.7%) of T types, 2 cases(28.6%) of B types and 17 cases(27.9%) of L types of leprosy. 2. In the L type of leprosy, infiltration of foamy cells showed elongated(63.9%) or nodular(27.9%) patterns more than typical diffuse infiltrative pattern(8.2%). 3. Selective nerve involvement by lymphocytes was found in 2 cases of L types of leprosy. 4. In the B type and the L type leprosy, prominent nerve involvement and neural destruction was not found in 1 and 7 cases, respectively and sparse to mild infiltration of foamy cells was found in 71.4% and 34.4%, respectively. Conclusion : In the histopathological diagnosis of T type leprosy, elongated or even round granuloma, perineurial lymphocytic infiltration and nerve remnant in the granuloma was characteristic. As for L type of leprosy, we should know that in 1/3 cases, it can show only sparse to mild infiltration of foamy cells and there is no obvious nerve abnormalities. Therefore, these results suggest that many cases of leprosy can show atypical histopathological findings and we should take caution in the diagnosis of leprosy. (Korean J Dermatol 2003;41(8) : 1049~1056)
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김소연 ( Kim So Yeon ),조영은 ( Jo Yeong Eun ),최유원 ( Choe Yu Won ),황규광 ( Hwang Gyu Gwang ),함정희 ( Ham Jeong Hui ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.10
Osteoma cutis is a rare disorder characterized by compact bone formation in the dermis and subcutaneous tissue. It is classified in primary and secondary forms according to the presence or absence of previous cutaneous lesions. Multiple miliary osteomas of the face is a form of primary miliary osteoma cutis that generally occurs in middle-aged and older women. We report a typical case of multiple miliary osteomas of the face in a 63-year-old woman.(Korean J Dermatol 2003;41(10) : 1378~1380)
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