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이선영 ( Lee Seon Yeong ),김재준 ( Kim Jae Jun ),최원혁 ( Choe Won Hyeog ),이준행 ( Lee Jun Haeng ),김영호 ( Kim Yeong Ho ),손희정 ( Son Hui Jeong ),이풍렬 ( Lee Pung Lyeol ),이종철 ( Lee Jong Cheol ),기창석 ( Gi Chang Seog ),김 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> 위암에서의 유전자 불안정성 변이는 잘 알려졌으나 임상적, 병리학적 소견에 따른 유전자 불안정성 (microsatellite instability; MSI)에 대해서는 이견이 많다. 이에 저자들은 위 선암의 MSI를 조사하여 임상적, 병리학적 소견과의 연관성을 검토하였다. <대상 및 방법> 장형과 미만형 위암으로 진단받은 환자들의 위 절제표본을 나이와 성별에 맞추어 각각 14증례씩 수집하였다. MSI는 PCR 증폭과 자동 DNA sequencin
김흥업 ( Kim Heung Eob ),김영호 ( Kim Yeong Ho ),최원혁 ( Choe Won Hyeog ),김정환 ( Kim Jeong Hwan ),육청미 ( Yug Cheong Mi ),이재욱 ( Lee Jae Ug ),심상군 ( Sim Sang Gun ),손희정 ( Son Hui Jeong ),이풍렬 ( Lee Pung Lyeol ),김재준 대한소화기학회 2003 대한소화기학회지 Vol.42 No.5
In western countries, symptomatic diverticulitis develops in about 20% of the population with colonic diverticula, and it is mainly located at the left-sided colon. The clinical characteristics of diverticulitis have rarely been investigated although its incidence is increasing in Asia including Korea. The aim of this study was to compare diverticulitis with asymptomatic diverticulosis and to compare the clinical characteristics of right-sided diverticulitis with those of left-sided diverticulitis. Methods: We retrospectively investigated the medical records of the patients who had symptoms and signs of diverticulitis. Their diagnosis was confirmed with computed tomography, barium study, colonoscopy and/or operations at Samsung Medical Center from September 1998 to February 2002. The control cases of asymptomatic and incidental diverticulosis were randomly selected during routine health check-up after matching age and sex. Results: Twenty-seven patients with diverticulitis (male:female=14:13) were included. The mean age was 53 (27~86). The ratio of right and left diverticulitis was 20:7, which was similar to the ratio of diverticulosis. The complications, especially perforation, were more frequent in the patients with left-sided diverticulitis (p<0.05). Conclusions: Colonic diverticulitis is more prevalent at the right colon and left colonic diverticulitis has more complications than right colonic diverticulitis in Korea. (Korean J Gastroenterol 2003;42:363-368)