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알레르기 환자에서 면역료법 전후의 말초혈액 Fcε 수용체 보유 림프구의 변화
강영모(Young Mo Kang),허영구(Young Gu Hoe),최귀애(Gui Ae Choi),김항재(Hang Jae Kim),김능수(Nung Soo Kim) 대한내과학회 1989 대한내과학회지 Vol.37 No.6
N/A We studied the effect of immunotherapy on the pro- portion of Fcε receptor bearing cells [Fcε R(+) cells] in PB lymphocytes, serum IgE and PB T cells with their subsets in 18 allergic patients with asthma or rhinitis who were treated with effective immunotherapy (6 months to 12 months) and 16 untreated allergic patients. The proportion of Fcε R(+) cells in PB lymphocytes in immunotherapy-treated patients was significantly lower than that in untreated patients, even though both of those showed higher levels than the normal ranges. However, there were no significant differences in serum IgE levels and the proportions of T cells with their subsets in PB lymphocytes between the groups of immunotherapy-treated patients and untreated patients. These findings may suggest that the proportion of Fcε R(+) cells in PB lymphocytes could be one of the parameters to monitor the early immunological changes in effective immunotherapy.