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양전자방출단층촬영 ( PET ) 에서 회전 핀선원과 투과 및 방출 동시 영상 방법을 이용한 감쇠보정 방법 특성에 관한 고찰
김상은(S . E . Kim),이경한(K . H . Lee),이정림(J . R . Lee),최용(Y . Choi),지대윤(D . Y . Chi),신승애(S . A . Shin),김병태(B . T . Kim) 대한핵의학회 1995 핵의학 분자영상 Vol.29 No.4
N/A Attenuation correction is important in producing quantitative positron emission tomography (PET) images. Conventionally, photon attenuation effects are corrected using transmission measurements performed before tracer administration. The pre-injection transmission measurement approach may require a time delay between transmission and emission scans for the tracer studies requiring a long uptake period, about 45 minutes for F-18 deoxyglucose study. The time delay will limit patient throughput and increase the 1ikelihood of patient motion. A technique for performing simultaneous transmission and emission scans (T+E method) after the tracer injection has been validated. The T+E method substracts the emission counts contaminating the transmission measurements to produce accurate attenuation correction coefficients. This method has been evaluated in experiments using a cylindrical phantom filled with background water (5750 cc) containing 0.4 μCi/cc of F-18 fluoride ion and one insert cylinder (276 cc) containing 4.3 μCi/cc. GE AdvanceTM PET scanner and Ge-68 rotating pin sources for transmission scanning were used for this investigation. Post-injection transmission scan and emission scan were performed alternatively over time. The error in emission images corrected using post-injection transmission scan to emission images corrected using post-injection transmission scan to emission images corrected transmission scan was 2.6% at the concentration of 1.0 μCi/cc. No obvious differences in image quality and noise were apparent between the two images. The attenuation correction can be accomplished with post-injection transmission measurement using rotating pin sources and this method can significantly shorten the time between transmission and emission scans and thereby reduce the likelihood of patient motion and increase scanning throughput in PET.
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