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주연미 ( Yeonmi Ju ),이윤채 ( Yoon Chae Lee ),강미희 ( Mi Hee Kang ),서승영 ( Seung Young Seo ),김성훈 ( Seong Hun Kim ),조백환 ( Baik Hwan Cho ),유희철 ( Hee Chul Yu ),양재도 ( Jae Do Yang ),이승옥 ( Seung Ok Lee ) 대한췌장담도학회 2015 대한췌담도학회지 Vol.20 No.1
Background/Aims: Although the incidence of GB polyps is increasing with improved surveillance, the study of predictive factors of malignant potential has not been suffi cient. The aim of this retrospective study is to investigate the predictive factors of malignant potential in GB polyps. Methods: Among 3,159 patients with laparoscopic cholecystectomy in Chonbuk National University hospital January 2009 to December 2013, 437 patients confirmed GB polyps pathologically were enrolled. The patients were divided into two groups; one with benign GB polyp and another with GB adenoma and incidental GB cancer. Results: Group I with benign GB polyp was seen in 359 patients. On the other hand, 53 patients with GB adenoma and 25 patients with GB cancer in gourp II were identified. The patients in group II had shown a significantly higher incidence of age older than 50 years (53/78, 67.9% vs. 163/359, 45.4%, p=0.001), size larger than 10mm (40/78, 51.3% vs. 37/359, 10.3%, p<0.001), and GB wall thickening (36/78, 46.2% vs. 77/359, 21.5%, p<0.001). The presence of GB stone had not shown significant differences between two groups (26/78, 33.3% vs. 96/359, 26.7%, p=0.378). Conclusions: Cholecystectomy should be considered for the patients with GB polyp with these predictive factors.