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      저자 : 조준탁 ( Jo Jun Tag ) (검색결과 1 건)
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        유기인계 살충제 중독증에서의 혈청 Amylase 활성도

        이수기 ( Lee Su Gi ),이은경 ( Lee Eun Gyeong ),정지인 ( Jeong Ji In ),정정희 ( Jeong Jeong Hui ),조준탁 ( Jo Jun Tag ),이진관 ( Lee Jin Gwan ) 대한내과학회 1993 대한내과학회지 Vol.44 No.4

        Organophosphate insecticides are used allover the world and are household items in the rural area of the Korea. Because of their easy accessability, their ingestion either accidentally or for a suicidal purpose is common in the Korea. Acute pancreatitis occuring as a complication of an anticholinesterase insecticide intoxication was first reported by Dressel et al(1979) and has since been reported by other investigators. Among them, pancreatitis with unresponsiveness followed by pseudocyst, or painless hemorrhagic pancreatitis only menifested by ileus and abcominal distension was founded after intoxication. We had serial serum amylase determination and clinical evaluation on 31 patients of organophosphate intoxication. The results were as follows. In the 31 patients of poisonous organophosphate insecticide, serum amylase was elevated in the 17 patients and was assumed to show pancreatic involvement. Btu, abdominal pain or ileus was absent. In 5 of 17 patients, serum amylase level was more than 500 U/dl and suggested to evoke acute pancreatitis. All of the 5 patients receive upper abdominal ultrasonography. In one patient, there was an edematious change in the body and tail of the pancreas and normalized in the following study. Others were normal. Severely affected patients who needed respiratory assistance and had mental change, mean serum amylases value was the hightest and the possibility of acute pancreatitis was the greatest. In our study, forfunately, all the patients discharged without complication of acute pancreatitis. Therefore, in the patients of organophosphate insecticide intoxication, if ileus or suspicious peritonitis is presents, we must consider the development of acute pancreatitis.

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