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        성 Hormone 의 투여가 하수체척출 흰쥐의 생식선에 미치는 영향

        이규승,정영채 . 김관영 ( Kae S . Lee,Young C . Chung,Kwan Y . Kim ) 한국축산학회 1975 한국축산학회지 Vol.17 No.3

        To ascertain whether sex hormone affects directly on the gonad without the cooperation of hypophysis, rats were hypopysectomized and administered 6.0㎎ of various set hormones, hexestrol for female group and testosterone propionate for male group. The weight of gonads and histopathological alteration were compared with those of control, during the period from 1 to 56 days after hypophysectomy. The results were as follows; 1. No difference of the weight of gonad was observed between hypophyaectomized group and hypophysectomized group followed by sex hormone administration, but the weight of gonads of male and female groups were decreased after treatment and showed high significant difference from 7th day in female group and from 14th day in male group after treatment. 2. Although a marked degeneration of gonad was observed histopathologically in both male and female groups, no difference of the degeneration was found between hypophysectomized group and hypophysectomized and administered sex hormone group. This study indicate that sex hormone does not directly affect on the development of gonad, but cooperate with the function of hypophysis.

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