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초기 건선병변의 조직화학적 관찰 - 산성 점다당질 및 비반세포의 변동 -
차명훈(Myong Hun Cha),김종민(Jong Min Kim),이종주(Chong Ju Lee),노병인(Byung In Ro),장진요(Chin Yo Chang),송계용(Kye Yong Song) 대한피부과학회 1983 大韓皮膚科學會誌 Vol.21 No.5
Twenty-eight cases of initial psoriasis were studied with histochemical methods in an attempt to obtain changes of acid mucopolysaccharides and mast cells. Early psoriatic lesions (pin head sized) and clinically uninvolved skin at distances of 2-4crn from the psoriatic lesions were excised respectively. The results are as follows; 1. Dermal changes were more prominent than the epidermal changes in almost all specimens in early psoriatic lesions. The main features of the dermal changes were perivascular inflammatory infiltrate which were consisted mainly of lymphoid cells. 2. Inflammatory infiltrate in the region of epidermal a.lteration and papillary edema is par ticulary striking. R. Among the 26 cases, the amount of acid mucopalysaccharides of initial lesion was lesser in 14 cases, greater in 4 cases and same in 8 cases as compared with clinically normal skin. 4. The number of mast cells of initial psoriatic lesion as compared with clinically normal skin was increased(p <0. 01).
장준(June Chang),홍창권(Chang Kwun Hong),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1989 대한피부과학회지 Vol.27 No.6
To take advantage of hypertrichosis, one of the side effcct of minoxidil, is used as a application to male pattern baldness and alopecia areata. Recently 101 Hair Regrowth Liniment which is a new hair growth stimulator from China is used in male pattern baldness, but its components, actions and side effects are exactly unknown. We experienced three cases of allergic contact dermatits one case due to minoxidil and others due to 101 Hair Regrowth Liniment which were confirmed by patch test.
장준(June Chang),김명남(Myeung Nam Kim),송계용(Kye Yong Song),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.1
The nevus sebaceus of Jadsssohn is an organoid nevus generally noted on the scalp or the face as a single lesion. A 26-year-old man has suffered from a pea sized, pedunculated cherry red colored papule on the back ground of yellowish colored verrucous plaque on the vertex. Clinically, pedunculated papule was similar to granuloma pyogenicum, but histopathologic examination showed the features of tubular apocrine adenoma with focal areas of syringocystadenoma papilliferum, suggesting that might be a variant or could be associated with syringocystadenoma papilliferum. (Kor J Dermstol 28(1): 103 106, 1990)
두드러기 및 아토피 피부염 환자에서의 알레르겐 단자 시험 성적
민태형(Tae Hyung Min),홍창권(Chang Kwun Hong),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.5
This study was undertaken to investigate the skin sensitivity to 54 different allergens in 248 patients of 81 acute urticaria, 141 chronic urticaria and 26 atopic dermatitis, who visited in Department of Dermatology, College of Medicine, Chung Ang University Hospital from February 1986 to January 1987. The results were as follows . 1. The sex ratio of male to female of 248 patients with allergic state was 1.1: 1 (130: 118) and third and fourth decades occupied 56.5%. In regard to the duration of chronic urticaria, less than 1 year were 31.2% and between 1 to 3 years were 28.3%. 2. In acute urticaria, the prick test positive reactivity to allergens were in descending order to mite, household insect mixture, Trichophyton mixture, house dust, mold mixture C and silk, whereas in chronic urticaria ', mite, household insect mixture, house dust, cockroaeh mixture, Trichophyton mixture and silk and in atopic dermatitis ; mite, house dust, Trichophyton mixture, household insect mixture, mold mixture A and C. 3. The positive reactivities of allergens in patients with atopic dermatitis, chronic urticaria and acute urticaria were 69.2%, 52.5% and 35.8%, respectively. 4. The positive reactivity to compound allergens were higher than to single and the most frequent combinations were 2 to 5 allergens (85.4%). 5. Out of 54 allergens used in this study, 49 allergens were reactive and the most frequent group of allergens were house dusts (41.5%) and commonly involved allergens were mite (27.8%), household insect mixture (15.7%), house dust (13.7%), Trichophyton mixture (11.7%) and cockroach mixture(7.7%). 6. Common other allergic diseases combined with atopic dermatitis were rhinitis and bronchial asthma, occuring in 23.1%.
임기섭(Ghi Seob Lim),홍창권(Chang Kwun Hong),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1986 대한피부과학회지 Vol.24 No.6
Xeroderma pigmentosurn is a photosensitive hereditary disorder and especially rare in Korea. A 30-year old male patient had been suffered from walnut sized tumor and several ulcerated papules on the face, and scattered brownish macules on the sun-exposed area. Clinical features and histopathologic findings were consistent with malignant malanoma and basal cell epithelioma developing in a xeroderma pigmentosum respectively. Malignant melanoma was surgically excised.
만성 피부점막 칸디다증 - 증례 보고 및 문헌적 고찰 -
김명남(Myeung Nam Kim),홍창권(Chang Kwun Hong),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1986 대한피부과학회지 Vol.24 No.5
A 11-year-old girl with chronic mucocutaneous candidiasis(CMCC) has been observee since the age of 4 years. At first(November, 1978) there was a good response to treatment with amphotericin B intravenously of total 300 mg, but not to with oral administration of nystatin and local clotrirnazole cream. Since that time, she bas been admitted on different occasions for further evaluation and therapy because of recurrences. During the most recent hospitalization in October, 1985, she was suffered from herpes zoster in addition to CMCC. We treatecl her with analgesics and intravenous globulin for herpes zoster, and concomitantly with ketoconazole(200 mg/day) and 5-fluarocytosine for 20 days. At the end of this period, she was free of any clinical evidences of CMCC and herpes zoster.
조윤화(Yoon Whoa Cho),홍창권(Chang Kwun Hong),송계용(Kye Yong Song),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.3
We report a case of X-linked ichthyosis in a 19 year-old male patient who has been covered with brown to black colored thick scales on the lateral aspect of chest, upper abdomen and inner aspect of both extremities since one month at, birth. Histopathologic findings showed hyperkeratosis and papillomatosis with normal granular cell layers in the epidermis. On electron microscopy, multilayered keratins with increased melanosomes in the stratum corneum were noted. In his family, his cousin is also affected by the same disease. (Kor J Dermatol 28(3): 368 372, 1990)
이주협(Joo Hyeup Lee),홍창권(Chang Kwun Hong),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.3
Generalized essential telangiectasia is defined as condition in which the veins and cspillaries of the skin undergo primary dilation independently of preceding or coexisting skin lesions of other types. We report herein a case of generalized essential telangiectasia in a 27-year-old female, who has been suffered from generalized erythematous to reddish linear, mottled, or net like telangiectatic macules except face, hands and feet. There were no abnormal laboratory findings and no evidence of systemic disease. Histopathologic examinations showed only dilated telangiectatic vessels in the upper dermis. (Kor J Dermatol 28(3): 385 389, 1990)
면역억제제를 사용하여 유천포창 치료 중 대상 포진이 발생된
임기섭(Ghi Seob Lim),홍창권(Chang Kwun Hong),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.5
A 47 year-old woman with generalized fresh tense or ruptured bullae was diagnosed as bullaus pemphigoid by histopathological and direct immunofluorescent test. We treated her with prednisolone and bethamethasone for 3 weeks. And soon after, herpes zoster developed along the right T9 dermatome. It is not precise whether true association or only incidental concomitance, but, there may be present some relatioship.
노병관(Byung Kwan Ro),원문섭(Moon Sup Won),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.3
The nail has been considered to be the best human model to evaluate the general body state at all ages. The present study was disigned to measure the nail growth rate and to define the correlation of them with other values of nail size. The subjects were 373 males and 812 females whose ages from R months to 79 years. The results were as follows: 1. The linear elongation of the nails were most rapid in the 14 to 15 year-old age group. It decreased steadily as the subjects got older and olr1er. 2. Sex differences in the nail growth rate were not statistically significant. R. Where were no statistically significant differences in the linear growth rate of nails between right and left hands. 4. The middle finger nail grew more quickly than others, while the thumb and little finger nails grew more slowly. 5. Linear growth of nails were not significantly correlated to the thickness and length of nails and the length of lunulae.