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노인 입원 환자에서 섬망 발생과 결과에 대한 후향적 연구
임채성(Chaesung Im),차승민(Seungmin Cha),김재헌(Jaeheon Kim),이재민(Jaemin Lee),김정란(Jeong Lan Kim) 대한생물치료정신의학회 2012 생물치료정신의학 Vol.18 No.2
Objectives:This study was aimed to examine the development and outcome of delirium in elderly inpatients retrospectively. Methods:We reviewed medical records of 2,570 patients, who were referred to consultation of psychiatry between January 2007 and December 2011. We found 916 patients(35.6%) who were confirmed as delirium by psychiatrists with DSM-IV-TR diagnostic criteria. The epidemiologic and clinical information were obtained and the factors affecting on recovery and recurrence of delirium were explored. All statistical analyses were conducted by using Pearson Chi- Square test, Student`s t-test, Binary logistic regression analysis with SPSS 17.0. Results:916 patients presented delirium. 577 patients(63.0%) were men and 339 patients(37.0%) were women. The mean of age was 74.6 years. The most frequently prescribed medicine was risperidone(52.7%), and followed by quetiapine(26.8%), olanzapine (9.9%). We found significant differences in Sex, Age, Ambulation state and Treatment in recovered and unchanged patients group. Additionally we also found that male sex can be a risk factor of recurrent delirium(OR 1.914, CI 1.102-3.323). Conclusion:These results suggest that female, advanced age, ambulation and antipsychotic medication can be associated with positive outcome of delirium, whereas male can increase the risk of recurrence of delirium.