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      • KCI등재

        면역전기영동법에 의한 자궁경관점액중의 혈청단백에 대하여

        박제우(JW Park),권영조(YJ Kwon),임수덕(SD Lim) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.11

        In recent years the analysis of the protein components in the cervical mucus has drawn more attention with respect to the possible occurrence of a biologic infertility cause by an immune reaction between sperm antigen and cervical mucus antibodies, and antimicrobial prophyractic immunity. Immunoelectrophoretic studies on cervical mucus have already been undertaken by several workers, but there is not complete agreement as regards to proteins in cervical scretions obtained from nonpregnant women as yet probable due to differences in techniques used. It was the purpose of this study to investigate in single, undiluted specimens the appearance of serum proteins in cervical mucus of Korean women during different stages of the menstrual cycle. Summary 1) A complete study of the proteins of normal cervical mucus has been made by immunoelectrophoresis in cases of Korean women. 2) Albumin, transferrin, and gamma globulin(IgG) were always found, and in the half of the cases alpha-2 globulin and IgA were present. 3) No significant differences in protein component of cervical mucus were found in regard to menstrual cycle. 4) The possible role of cervical mucus(especially, IgG and IgA) in the production of biological infertility and antimicrobial prophylactic immunity was discrssed together with the limits and merits of the immuno elctrophoretic method in the study of the cervical mucus.

      • KCI등재

        한국인 모유에 관한 면역학적 연구 ( 제1편 ) 초유에 함유된 Immunoglobulin의 정량분석

        권영조(YJ Kwon),이성근(SK Lee),임수덕(SD Lim) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.11

        Comparative and immunochemical analyses of the milk and serum immunoglobulins IgG, IgA&IgM were attempted in a series of experiments. In this paper, quantitative meaurements of the immunoglobulins in the colostrum and maternal serum using Oudin`s capillary tube technique were presented. Smaples were obtained from 21 normal Korean puerperas, totalling 21 colostrums and 11 maternal sera. Levels of the immunoglobulins in the colostrum were: IgG 118.2 64.35mg%, IgA 334.9 162.2mg%, IgM 50.4 23.1mg%,: and those of maternal sera were: IgG 1,979.1 702.5mg%, IgA 227.6 43.1mg%, IgM 88.4 15.2mg%. The high concentration of IgA immunoglobilin in the colostrum was most noticeable finding. In addition to the experiments, recent findings and knowledsge about the immunoglobulins were also described.

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