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      • 표면 강성이 세포 형태 및 운동성에 미치는 영향

        이우택(Wootaek Lee),오지우(Jiwoo Oh),송석현(Sukhyun Song),남아현(Ahhyun Nam),신현정(Jennifer H. Shin) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11

        Cell physiology is regulated extensively by biochemical factors. However, recent studies have identified many types of mechanosensitive cells to address the importance of mechanical cues in cell functions and motility. While extensive work exists on the effect of adhesive proteins on cells motility, little is known about how motility of cells is affected by the mechanical properties of their physical environment. The effects of substrate stiffness on the morphology and motility speed of 3 different cells have been investigated. Human dermal fibroblast, human keratinocyte HaCaT cell and human aortic endothelial cell (HAEC) were plated onto PDMS of varying stiffness, ranging from 10 ㎪ to 1.5 ㎫, and coated with the fibronectin. Our results show that there is an optimal migration stiffness range of each cell type. The modulation of mechanical cues such as altering the rigidity of cell environment may be the key mechanism used to regulate cell migration and wound healing.

      • KCI등재SCOPUS

        승용차의 도심 주행패턴에 관한 연구

        정남훈(Namhoon Chung),이우택(Wootaek Lee),선우명호(Myoungho Sunwoo) 한국자동차공학회 2003 한국 자동차공학회논문집 Vol.11 No.1

        Vehicle emission is one of the major sources of air pollution, and provides some undesirable effects on the atmospheric environment and human health. In this study, the driving data were recorded during road tests in Seoul metropolitan area, and analyzed by statistical techniques. The objective of the study is to analyze the driving patterns of passenger car that influence on emissions in urban driving. The results show that the average speed is around 29.9km/h, and the average fuel economy is 10.23 km/ ?? . The vehicle speed of Seoul metropolitan area is slower, and the stop-and-go operation is more frequent than CVS-75 test mode which is used for emission and fuel economy test.Vehicle emission is one of the major sources of air pollution, and provides some undesirable effects on the atmospheric environment and human health. In this study, the driving data were recorded during road tests in Seoul metropolitan area, and analyzed by statistical techniques. The objective of the study is to analyze the driving patterns of passenger car that influence on emissions in urban driving. The results show that the average speed is around 29.9km/h, and the average fuel economy is 10.23 km/ ?? . The vehicle speed of Seoul metropolitan area is slower, and the stop-and-go operation is more frequent than CVS-75 test mode which is used for emission and fuel economy test.

      • KCI등재SCOPUS

        승용차 도심 주행패턴에 의한 연비 성능 분석

        정남훈(Namboon chung),이우택(Wootaek Lee),선우명호(Myoungho Sunwoo) 한국자동차공학회 2003 한국 자동차공학회논문집 Vol.11 No.1

        There are a lot of factors influencing on the automobile fuel economy such as average speed, average acceleration, acceleration sum per kilometer, and so on. In this study, various driving data were recorded during road tests. The accumulated road test mileage in Seoul metropolitan area is around l,300 kilometers. The data were analyzed by multivariate statistical techniques including correlation analysis, principal component analysis, and multiple linear regression analysis. The analyzed results show that the average trip time per kilometer is one of the most important factors to fuel consumption and the increase of the average speed is desirable for reducing emissions and fuel consumption.

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