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신장이식 후 Cyclosporine 사용 중 발생한 조증환자에 대한 Olanzapine 치험례
이산수(Sansoo Lee),이상열(Sangyeol Lee),홍정완(Jeongwan Hong) 대한생물치료정신의학회 2008 생물치료정신의학 Vol.14 No.2
We present the case of a 43-year-old woman with no previous diagnosis of bipolar disorder who underwent kidney transplantation for end stage renal disease. 7 years post-transplant, she exhibited manic symptoms including hyperactivity, elated mood, decreased need for sleep, grandiose and religious delusion, and pressured speech. Most reports about treatment of postoperative psychiatric problem-especially corticosteroid induced mood disor-der-have emphasized the use of Lithium, typical antipsychotics. We found a few case reports in which atypical antipsychotics were prescribed for those case but there is no one in which olanzapine was prescribed in a kidney transplanted patient. Olanzapine is an atypical anti psychotics which has antimanic and mood-stabilizing as wall as sedative properties. And we reasoned that this agent might be useful for the treatment of mania in a kidney transplanted patient who is taking cyclosporine, and we report a case that the olanzapine treatment was successful in the transplanted patient with manic episode.