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감염 : 반복하여 재발한 류마티스 결절증(nodulosis) 1예
이슬기 ( Seul Kee Lee ),유쾌한 ( Kwai Han Yoo ),이걸 ( Keol Lee ),김인영 ( In Young Kim ),권희진 ( Hee Jin Kwon ),차훈석 ( Hoon Suk Cha ),황지원 ( Ji Won Hwang ) 대한내과학회 2015 대한내과학회지 Vol.88 No.2
Rheumatoid nodulosis, a benign variant of rheumatoid arthritis (RA), is a rare condition characterized by multiple subcutaneous nodules and positive rheumatoid factor in the absence of systemic manifestations or joint disease. Asymptomatic nodules rarely require treatment, and are unlikely to recur after excision, except in cases in which RA develops. Here, we describe an unusual case of recurrent rheumatoid nodulosis in a 42-year-old female presenting with recurrent subcutaneous nodules on the plantar side of her left foot, which caused pain when walking. Nodules were initially excised to control symptoms; however, since the excision, the nodules have recurred twice in the absence of other RA symptoms. (Korean J Med 2015;88:241-245)
증례 : 류마티스 ; 전신경화증과 류마티스 관절염의 중복 증후군 3예
이슬기 ( Seulkee Lee ),유쾌한 ( Kwai Han Yoo ),이걸 ( Keol Lee ),김인영 ( In Young Kim ),권희진 ( Hee Jin Kwon ),정혜민 ( Hyemin Jeong ),고은미 ( Eun Mi Koh ) 대한내과학회 2015 대한내과학회지 Vol.88 No.3
저자들은 전신경화증을 가지고 있던 환자 중 다발성 관절염으로 내원해 류마티스 관절염과의 중복 증후군으로 진단된 환자 3예를 경험했기에 문헌고찰과 함께 보고하는 바이다. Overlap syndrome is defined as a disease entity that fulfills the classification criteria of at least two different rheumatologic diseases simultaneously. Overlap of systemic sclerosis (SSc) and rheumatoid arthritis (RA) is less common than the overlap of polymyositis with SSc or systemic lupus erythematosus. Distinguishing RA from SSc can be difficult because arthralgia is a frequent symptom of both. We observed three cases of RA and SSc overlap. In each case, RA occurred in sequence with SSc, with a period of 4-15 years between the onset of each disease. In one case, the patient had diffuse SSc, which is rare among overlap syndrome patients. Previously, only one case of overlap syndrome involving SSc and RA has been reported in Korea; herein, we report our cases with a review of the literature. (Korean J Med 2015;88:350-355)