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A549 폐암세포와 Sarcoma-180 복강암에 대한 인삼(人蔘) 증류약침(蒸溜藥鍼)의 영향에 관(關)한 실험적(實驗的) 연구(硏究)
위종성,권기록,박희수,We, Jong-Seong,Kwon, Ki-Rok,Park, Hee-Soo 대한약침학회 2004 Journal of pharmacopuncture Vol.7 No.3
Objectives : In order to investigate effects and immune improvement of distilled white-ginseng herbal extract, expression of Cox-1, Cox-2, and mRNA of Bcl-2 and Bax were analyzed in A549 cell in vivo. Survival time and expression of cytokine mRNA were measured for the mice with Sarcoma-180 induced abdominal cancer. Methods : Balb/c mouse was treated with distilled white-ginseng Herbal Acupuncture at Wisu($Bl_{21}$) and Chung-wan($CV_{12}$) to investigate anti-cancer effects and immune response. Results : 1. For expression of mRNA of Cox-1 using RT-PCR. the control group and the experiment groups show significant increase. For Cox-2, both experiment groups and the normal group showed significant decrease. For Bcl-2, experiment groups showed slight decrease compared to the control group. For Bax, no significant changes were shown between the control group and experiment groups 2. For survival time, all of experiment groups didn't show significant differences. 3. IL-2 productivity using Flow cytometry, experiment group I didn't show any significance, For II-4, all of experiment groups showed slight decrease compared to the control group. 4. For IL-2 productivity using ELISA, experiment group I showed slight decrease compared to the control group, experiment group II didn't show any significance. 5. For expression of cytokine mRNA using RT-PCR, significant increase of IL-2 and IL-4 were witnessed in experiment group I compared to the control group. Significant decrease of IL-10 was shonwn in all of experiment groups compared to the control group. Conclusion : According to the results, we can expect that distilled white-ginseng Herbal Acupuncture may be further effects in anti-cancer and immune improvement if increasing concentration.
박원형 ( Won Hyung Park ),이석원 ( Seok Won Lee ),차윤엽 ( Yun Yeop Cha ),위종성 ( Jong Seong We ) 한방재활의학과학회 2004 한방재활의학과학회지 Vol.14 No.1
Objectives: We got a good effect on one patient who was diagnosed piriformis syndrome. Methods: We used acuputure and ischemic compression on the piriformis muscle. The others were Herbal medication and physical therapy. We measured the ROM(Range of motion) of Lumbar and VAS(Visual Analog Scale). Results: Patient`s chief complain is right leg radiating pain and low back pain. After treatment, most symptoms decresed and ROM, ambulation improved. VAS score changed from 10 to 2 for two weeks. Conclusions: The symptoms of piriformis Syndrome were successfully treated by acuputure and ischemic compression on piriformis muscle.