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김영훈 ( Kim Yeong Hun ),심성곤 ( Sim Seong Gon ),조경란 ( Jo Gyeong Lan ),김진배 ( Kim Jin Bae ),이오영 ( Lee O Yeong ),최호순 ( Choe Ho Sun ),함준수 ( Ham Jun Su ),이민호 ( Lee Min Ho ) 대한소화기학회 2003 대한소화기학회지 Vol.42 No.5
The colonic transit time in patients with liver cirrhosis has not been studied extensively in South Korea. Thus, the authors investigated the differences of colonic transit time between cirrhotic patients and normal controls with attention to factors that affect this change. Methods: Fifteen cirrhotic patients and 15 controls were included in this study. To exclude any organic diseases, colonoscopy was preceded. The colonic transit time was measured by taking plain abdominal films on the 4th and 7th days after ingestion of radiographic non-absorbable colon markers for 3 days. Results: The colonic transit time was 10.7±2.6 hours and 24.0±4.1 hours for cirrhotic patients and controls, respectively, indicating that the transit time in cirrhotic patients is much faster (p<0.05). The transit time for each segment of the colon was also measured. For the ascending colon, average transit time of the cirrhotic patients and controls were 5.60±1.93 and 6.88±1.77 hours respectively. For the descending colon, those were 2.80±1.04 and 10.80±2.59 hours (p<0.05), while those in the rectosigimoid portion were 2.32±0.81 and 4.96±1.19 hours, respectively. These results indicated that a significant difference is present in the descending colon. Additionally, the transit time is correlated with age and albumin level (B=0.760, p<0.05 and B=7.498, p<0.01, respectively). Conclusions: The colonic transit time of cirrhotic patients is faster than that of control, especially in the descending colon. (Korean J Gastroenterol 2003;42:394-399)