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      • SCOPUSKCI등재

        인지 기능 수행 시 BOLD 신호 크기에 기반 한 영역별 대뇌 편측화

        정순철(Soon Cheol Chung),손진훈(Jin Hun Shon),김익현(Ik Hyeon Kim),이수열(Soo Yeol Lee) Korean Society for Precision Engineering 2005 한국정밀공학회지 Vol.22 No.1

        This study compared cerebral lateralization index based on the area of neural activation with that based on the intensity of neural activation. For this purpose, 8 right-handed male college students (the mean age - 23.5 years) and 10 right-handed male college students (the mean age - 25.1 years) participated respectively in researches on visuospatial and verbal task brain function. Functional brain images were taken from 3T MRI using the single-shot EPI method. The result of measuring cerebral lateralization index based on the area of neural activation suggested that the right hemisphere is dominant in visuospatial tasks and the left one is in verbal tasks. However, the dominance is not sufficient to locate the exact part of the brain for these tasks. When cerebral lateralization index was computed based on the intensity of neural activation, it was derived that the area of cerebral lateralization closely related to visuospatial tasks is the superior parietal lobe, and the area of cerebral lateralization closely related to verbal tasks is the inferior and middle frontal lobes. Thus, cerebral lateralization index by area based on the intensity of neural activation as proposed by this study can determine the dominance of the cerebrum by area, so is helpful for accurate and quantitative determination of cerebral lateralization.

      • SCOPUSKCI등재

        산소 공급으로 유발된 공간 인지 능력, 혈중 산소 농도, 심박동율의 변화

        정순철(Soon Cheol Chung),손진훈(Jin Hun Shon),이봉수(Bongsoo Lee),이수열(Soo Yeol Lee) Korean Society for Precision Engineering 2005 한국정밀공학회지 Vol.22 No.1

        Changes in visuospatial cognitive performance, blood oxygen saturation and heart rate due to the highly concentrated oxygen administration were observed in this study. Six male (25.8 ± 1.0) and six female (23.8 ± 1.9) adults were asked to perform 20 visuospatial tasks with the same level of difficulties by supplying two different oxygen levels (21%, 30%). Experiment consisted of Rest1 (1 min.), Control (I min.), Task (4 min.), and Rest2 (4 min.) and physiological signals such as blood oxygen saturation and heart rate were measured through each stage. The result showed the accuracy of task performance increased significantly at 30% oxygen concentration compared with 21 %, which means oxygen supply has positive effects on visuospatial cognitive performance. When 30% oxygen was supplied, blood oxygen saturation during control and task phases was increased and heart rate was decreased compared with 21 %. It means that 30% oxygen can stimulate brain activities by directly increasing the actual level of blood oxygen concentration during cognitive performance, and enough oxygen supply during cognitive performance make heart rate decrease.

      • SCOPUSKCI등재

        고농도의 산소 공급이 공간지각 과제 수행 시 젊은 성인 남자의 대뇌 편측화에 미치는 영향

        정순철(Soon Cheal Chung),손진훈(Jin Hun Shon),김익현(Ik Hyeon Kim) Korean Society for Precision Engineering 2004 한국정밀공학회지 Vol.21 No.8

        The present study attempted to investigate the effects of supply of highly concentrated (30%) oxygen on human ability of visuospatial cognition and cerebrum lateralization, compared to air of normal oxygen concentration (21 %). The experiment consisted of two runs, one for visuospatial cognition test with normal air (21 % of oxygen) and for visuospatial cognition test with more oxygen in the air (30% of oxygen). Each run was composed of four blocks and each block included eight control tasks and five visuospatial tasks. Functional brain images were taken from 3T MRI using the single-shot EPI method. The result of task performance showed the accuracy increased at 30%s concentration of oxygen rather than 21 %s. There were more activations observed at the left and right hemisphere, but there was decrease cerebrum lateralization with 30% oxygen administration. Thus, it is concluded that the positive effect on the visuospatial cognitive performance level by the highly concentrated oxygen administration was due to increase of cerebrum activation and decrease of cerebrum lateralization.

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