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알레르기접촉피부염 환자(영서지역, 2005~2010년)의 첩포검사(TRUE Test) 결과에 관한 고찰
설근동 ( Geun Dong Sul ),이성율 ( Sung Yul Lee ),김재홍 ( Jae Hong Kim ),홍한나 ( Han Nah Hong ),천재순 ( Jae Sun Chun ),안성구 ( Sung Ku Ahn ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.7
Background: Since 2005, the commercial patch test panel, the TRUE-test, has been available. However, there have been no reports regarding the results of the TRUE-test compared with previously used Korean Standard Series in Korea. Objective: This study aimed to evaluate the prevalence of the contact allergy, causative allergens, and source of allergens in patients who were diagnosed with allergic contact dermatitis, and to compare the findings with previously used Korean Standard Series. Methods: We reviewed the results of the TRUE-test from 2005~2010 in Wonju Christian Hospital. We patch-tested 843 patients who were diagnosed with allergic contact dermatitis. The patch test reading was performed on day 2 and days 3 or 4, according to the patients` needs. Epidemiologic findings of patients and the results of the patch tests were analyzed. Results: A total of 843 patch-tested cases were compiled and analyzed. Of 843 patch-tested patients (male, 309; female, 534), 65.8% had at least 1 positive reaction and 30.2% at least 2 positive reactions. The highest age distribution was the 5th decade in females. The face, with the exception of the eyelids, ears, and lips, was the most frequently affected site (comprising 50.3%). The highest sensitization rates were found with nickel (29.1%), thiomersal (10.9%), and cobalt dichloride (9.7%). The lowest positivity included caine mix (0.7%), mercaptobenzothiazole (1.2%), and quinolone mix (1.2%). Metal allergens displayed higher positive rates than any other standard allergens. The overall prevalence was similar with a recent report in Korea. Conclusion: There was no significant difference in the overall prevalence of the most sensitized allergen compared with the reports about previously used Korean standard series.