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Calcium carbonate와 fibrin adhesive의 병용이 성견 2급 치근 분지부 치주조직 재생에 미치는 영향
서은표,정현주,김영준,Seo, Eun-Pyo,Chung, Hyun-Ju,Kim, Young-Jun 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.2
The purpose of this study was to evaluate the effect of fibrin tissue adhesive and porous resorbable calcium carbonate on the periodontal regeneration of the class II furcation defect in dogs. Class II furcation defect was surgically created on the second, third, and fourth premolars bilaterally in the mandibles of six mongrel dogs. The experimental sites were divided into four groups according to the treatment modalities: Control-surgical debridement only; Group I-calcium carbonate grafting; Group II-application of fibrin adhesive only; Group III-application of fibrin adhesive after calcium carbonate grafting. The animals were sacrificed at the 2, 4, and 12 weeks after periodontal surgery and the decalcified specimens were prepared for histological and histometrical examination. The results are as follows : Clinically, there were no inflammatory response in all groups after 2, 4, 12 weeks. In the Control group, junctional epithelium was grown downward to the reference notch. In Group I, graft materials were exfoliated from the defect throughout the experimenta periods andnew bone was seen in the notch area at 4 and 12 week specimens. In Group II, fibrin adhesive was absorbed at 2 week specimens, and connective tissue attachment increased than that of control group. New cementum and new bone were seen above the notch area. In Group III, the graft material was maintained in the defect throughout the experimental period and inducing the amount of periodontal tissue regeneration was higher than other groups. These results suggest that the use of fibrin tissue adhesive in conjunction with porous resorbable calcium carbonate would improves the stability of graft material and inhibit the epithelial down growth and make it be a feasible method for periodontal regeneration.
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Calcium Carbonate와 fibrin adhesive의 병용이 성견 2급 치근분지부 치주조직 재생에 미치는 영향
서은표,정현주,김영준 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1
The purpose of this study was to evaluate the effect of combined use of fibrin tissue adhesive and porous resorbable calcium carbonate on the periodontal regeneration of the class Ⅱ furcation defects in dogs. Class Ⅱ furcation defect was surgically created on the second, third, and fourth premolars bilaterally in the mandibles of six mongrel dogs. The experimental sites were divided into four groups according to the treatment modalities: Control-surgical debridement only; GroupⅠ-calcium carbonate grafting; Group Ⅱ-application of fibrin adhesive only; Group Ⅲ-application of fibrin adhesive after calcium carbonate grafting. The animals were sacrificed at 2, 4, and 12 weeks after periodontal surgery and the decalcified specimens were prepared for histologic and histometric examination. The results are as follows : Clinically, there were no inflammatory response in all groups after 2, 4, and 12 weeks. In the Control group, junctional epithelium migrated apically to the reference notch. In Group Ⅰ, graft materials exfoliated from the defect throughout the experimental periods and new bone was seen in the notch area at 4 and 12 weeks' specimens. At 2 weeks, fibrin adhesive was indistinguishable in Group Ⅱ. In Group Ⅲ, the graft material was maintained in the defect throughout the experimental periods and the amount of periodontal tissue regeneration was greater than other groups. These results suggest that the use of fibrin tissue adhesive in conjunction with porous resorbable calcium carbonate would improve the stability of graft material and inhibit the epithelial downgrowth and contribute to periodontal regeneration.
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