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배정식(Jung Sik Bae),김동철(Dong Chul Kim),전신수(Sin Soo Jeun) 대한두개저학회 2009 대한두개저학회지 Vol.4 No.1
Chordoid meningioma is a rare variant of meningioma. That is classified as a grade Ⅱ tumors by world health organization classification due to a high rate of recurrence. We present a 61 year-old male patient harboring a chordoid meningioma without systemic hematologic disease. The tumor was located at the left infra and supra-tentorium. Histological examination of supratentorial mass demonstrated a finding compatible with a chordoid meningioma. We present this rare chordoid meningioma in the conception of it’s rarity and particular clinical manifestations associated with hematologic disease.
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임상 : 상모양세포성별세포종; 20명 환자들의 임상적 특징과 결과
허정우 ( Jung Woo Hur ),배정식 ( Jung Sik Bae ),양승호 ( Seung Ho Yang ),전신수 ( Sin Soo Jeun ),박춘근 ( Chun Kun Park ),김문찬 ( Moon Chan Kim ) 대한뇌종양학회 2011 대한뇌종양학회지 Vol.10 No.2
Objective: Most pilocytic astrocytomas (PA) are benign tumors. However, there can be a bad outcome according to the patient`s age, the degree of tumor resection and the location in which the established outcomes have not yet been reported. We therefore analyzed and evaluated the outcome and features of PAs in a retrospective study. Methods: We retrospectively analyzed 20 patients who were treated at our hospital between 1995 and 2009. Age, Karnofsky Performance Scale (KPS) score, tumor location, the degree of tumor resection, tumor recurrence or malignant transformation, the disease progression-free survival (PFS) rate and the overall survival (OS) rate were examined. Results: The mean age of the patients was 18.0±13.6 years. The mean PFS and OS rates were 53.3±49.2 months and 62.7±52.1 months. Twelve patients were less than 16 years of age and 8 patients were 16 years of age or older with the mean PFS rates 72.4±52.7 months and 24.6±25.5 months, respectively. Nine patients (45%) had tumor recurrence or progression and the mean PFS rate was 41.3±37.2 months. Among the recurrence group, the patients younger than 16 (5 cases) had a longer mean PFS (65.8±34.3 months) than the patients who was 16 or older (4 cases ; 11.8±12.2 months). Other factors did not show statistically significant differences in the PFS and OS rates. Conclusion: Generally, PA patients have a good prognosis. However, a bad prognosis can occur in adult patients, particularly with incomplete resection. Therefore, aggressive operations should be performed to prevent recurrence in older patients. Additionally, even though radical tumor resections are done, we should be aware of tumor recurrences, especially within the first 4 years after the operation.
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