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신경섬유종증이 동반된 산모에서 발생한 척추동맥 동맥류와 자간전증 1 예
오영미(Young Mi Oh),고민석(Min Suk Koh),여정(Jung Eun Yeu),박창서(Chang Sue Park),조성진(Sung Jin Cho) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.6
Neurofibromatosis is a complex hereditary disease involving many organs and systems. The incidence in pregnancy is less frequent and has been reported as 1/5000 to 1/18500 deliveries. Therefore, little is known about the interactions between neurofibromatosis and pregnancy. A survey of relevant literature suggests that patients with NF have an increased risk of perinatal complications (pregnancy induced hypertension, IUGR, preterm labor, abortion, stillbirth, high cesarean section rate) and maternal disease aggravation (rupture of an aneurysm, sarcomatous degeneration of neurofibroma, activation of pheochromocytoma). Refined ultrasound, flow studies and fetal monitoring allow us to provide improved pregnancy care for neurofibromatosis. However, It should be remembered that even now, neurofibromatosis places pregnant women and their fetuses in a high risk group with the potential to develop life threatening complications. We report a case of vertebral artery aneurysm and preeclampsia complicating a pregnancy with neurofibromatosis.
신재국(Jae Kook Shin),김학준(Hag Joon Kim),임병도(Byeong Do Lim),정의식(Eu Sik Jung),박창서(Chang Sue Park),조성진(Sung Jin Cho) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.10
Aplasic anemia is an extremely rare disease characterized by hypocellular bone marrow with fatty infiltration and peripheral blood pancytopenia. For over half of patients, no cause can be determined and the causal relation between aplastic anemia and pregnancy is not yet clear. Aplastic anemia in pregnancy is difficult to the obstetrician managing it because the risk of bleeding and infections are high and mortality in aplastic anemia associated with pregnancy is more than 20%. However, with improved treatment modalities and close clinical collaboration of hematologist and obstetrician, aplastic anemia complicated in pregnancy is becoming more frequent with favorable outcome. We experienced a case of aplastic anemia initially detected during pregnancy who was managed with intensive hematological support leading to delivery a healthy infant vaginally. We report this case with a brief review of the literature.