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이기환 ( Ki Whan Lee ),박이호 ( Yi Ho Park ),서주영 ( Choo Young Suh ) 대한내과학회 1968 대한내과학회지 Vol.11 No.5
An increased incidence of hyperuricemia in patients with hypertension has been cited in several reports. Hyperuricemia in hypertension results from diminished renal excretion of urate. We were conducted to study serum uric acid in 130 hypertensive patients and 95 normal persons, and the following conclusions were made. In the hypertensive patients, primary hypertension was 101, renal 19, and malignant 10. Normal serum uric acid value was, 4.25±1.47㎎./100ml. In man and 3.85±1.23㎎./100ml. In woman. A value for serum uric acid was arbitrarily termed to be elevated, if it exceeded 5.8㎎. /100ml. In males and 5.1㎎./100. in females. 97(75%) of 130 hypertensive patients were hyperuricemic, 70 (69%) of 101 patients with primary hypertension, 18 (95%) of 19 with renal hypertension and 9 (90%) of 10 with malignant hypertension had hyperuricemial. Incidence of hyperuricemia in the patients with hypertension sharply increased according to the severity of azotemia. An elevation of serum uric acid may be an early manifestation of a renal tubular dysfunction or is accompanied by other disturbance formed in the hypertensive patients.