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RISS 인기검색어
- 검색키워드
- 저자 : 박신성 ( Park Sin Seong ) (검색결과 1 건)
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함상수 ( Ham Sang Su ),김욱 ( Kim Ug ),박신성 ( Park Sin Seong ),서영일 ( Seo Yeong Il ),임성희 ( Im Seong Hui ),김병태 ( Kim Byeong Tae ),최문기 ( Choe Mun Gi ),장연복 ( Jang Yeon Bog ),유형준 ( Yu Hyeong Jun ),박성우 ( Park Seo 대한내과학회 1993 대한내과학회지 Vol.44 No.5
Backgrounds: To characterize tha IDDM in Korea, we analyzed the epidemiological and clinical features of DKA in 72 patients. Methods: Seventy-two cases thoses who met following diagnostic criteria were included in the analysis. 1) Clinical manifestation of typical DKA, 2)Blood glucise level>250 mg/dl, 3) Presence of ketonuria or keonemia, 4) Blood pH<7.34 Results: 1) The occurrence of DKA was higher in the young and infemale. 2) DKA occurred most frequently in colder season with apparent two peaks in March and December. 3) In 23.6%, DKA was the first clinical presentation of diabetes and in the remainders, diabetes wer known to be present for average of 5.4 years. 4) The most common precipitating factors of DKA was infection and omission of therapy was the next. No discernible precipitating factor was found in 26.4% of DKA cases. 5) Polyuria, polydipsia, dyspnea, nausea, vomiting and abdominal pain were frequent accompanying symptoms, and physical finding included Kussmaul breathing, tachycardia and hypotension. The mental stutus of patients were alert in 55.6% of DKA cases. 6) There was no significant difference in the body temperature, PB smear, and % of neutrophis between DKA cases with infection and those without infection. 7) On admission potassium was high in 43%, but low in 23% 6 hours after therapy. In only two-thirds of cases, fasting C-peptide level on admission was decreased in the range of classical IDDM. 8) Hypoglycemia was the most freqeunt complication during the treatment of DKA following by hypokalemia, hypernatremia, hyperkalemia, thromboembolism and ARDS. 9) Mortality of DKA was 13.9% and poor prognostic factors include old age, azotemia, associated bacterial pneumonia. Conclusions: The epidemiological and clinical feautures of DKA in Korea were similar to those in western countries, in respect to female preponderance, age, seasonal distribution, % of debut cases, precipitating fators, initial laboratory findings, complications, mortality and prognostic factors. This observation suggests that although the incidence rate of IDDM is low in Korea, there are cases that take clinical courses very similar to those of western countries.
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