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RISS 인기검색어
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- 저자 : 박성귀(Sung Kwi Park) (검색결과 3 건)
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각화극세포종과 편평상피세포암에서의 TGF - α 발현에 관한 비교 연구
박성귀 ( Sung Kwi Park ),장호선 ( Ho Sun Jang ),권경술 ( Kyung Sool Kwon ),정태안 ( Tae Ahn Chung ) 대한피부과학회 1996 大韓皮膚科學會誌 Vol.34 No.2
Background: Transforming growth factor-(TGF-a) is a acidic, heat-stable, 50 amino acid polypeptide which is related to cellular proliferation, malignant transformation, and angiogenesis. There are many similarities between keratoacanthoma(KA) and squamous cell carcinoma(SCC). So, it is often difficult to differentiate keratoacanthoma and squamous cell carcinoma, clinically and histologically. Objective : Our purpose was to examine the patterns of TGF-a expression on KA and SCC using immunohistochemical staining and to evaluate the usefulness of the immunohistochemical staining with antihuman TGF-a antibody on differentiation between KA and SCC. Methods : Formalin-fixed, paraffin-embedded specimens that had confirmed to KA(n=12) or SCC(n=10) were performed by immunoperoxidase staining with monoclonal antihuman TGF-a antibody Results : All of KA dmonstrated a diffuse pattern within tumor lobules, but, at the peripheral rim of cells, showed unstained pattern. In contrast to KA, 40% of the SCC had patchy infiltration within tumor lobules, and 60% of the SCC had diffuse pattern which was similar to the pattern found in KA. All of SCC showed well-defined staining at peripheral cells. Conclusion : Immunohistochemical staining with antihuman TGF-a antibody could be used on differentiation between KA and SCC. (Kor J Dermatol 1996;34(2): 227-232)
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박성귀(Sung Kwi Park),권경술(Kyung Sool Kwon),정태안(Tae Ahn Chung) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.2
Kaposis sarcoma(KS) is a multicentrically developing vascular neoplasm with four types of clinical manifestation. One of these, classic KS is clinically carmcterized by late onset, chronic course and radiosensitive. We report a case of classic KS in a 72-year-old male. This pateint complainted of purple patches and dark purple nxluk. on slightly edematous lower legs. The histopathologic sections from the lesional sites showed infiltration of spindle cells with newly formed vascular slits, dilated blood vessels and aggregated hemosiderins in the dermis. (Kor J Dermatol 1995;33(2): 369-373)
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권경술(Kyung Sool Kwon),한을희(Eul Hee Han),정태안(Tae Ahn Chung),임명규(Myeong Kyoo Lim),박성귀(Sung Kwi Park) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.2
A case report of a 60 year-old man with lichen aureus of leg is presented. Clinically the solitary golden to purple colored patch consists of lichenoid papules, plsque, and mild petechiae around the lesion, and the histology reveals a dense and bandlike infiltrate hugging thepidermis. It consists of lymphocytes, histiocytes, eosinophils, and many extravasated erythrocytes and hemosiderin in dermis, but a few red cells and increased melanin pigment can also be seen in the epidermis. The eruption is mildly itchy and has been present 6 months. (Kor J Dermatol 1994; 32(2): 342-315)
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