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유아에서 발생한 비정형 기형/횡문근양 종양 -증례보고-
문종언 ( Jong Un Moon ),김태성 ( Tae Sung Kim ),박봉진 ( Bong Jin Park ),임영진 ( Young Jin Lim ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2007 대한뇌종양학회지 Vol.6 No.2
Atypical teratoid/rhabdoid tumor(AT/RT) is extremely rare and highly malignant tumor of early childhood. AT/RT shows similar histopathological and radiological features to primitive neuroectodermal tumor(PNET) but more aggressive behavior than PNET. We report a case of supratentorial AT/RT with review of literatures. A 11-month-old female presented with a 2-weeks history of left side hemiparesis and convulsion. On neurologic examinations, there were no specific findings on developments and activities, except left side hemiparesis and intermittent seizure. Brain magnetic resonance images(MRI) revealed PNET such as primary cerebral neuroblastoma at right frontotemporal lobe with midline shift to the left side and suggestive of seeding nodule at occipital horn of left lateral ventricle. There were no evidences of spinal metastasis. Right frontotemporal mass was subtotally removed. Symptoms and signs were mildly improved but seizure was continued. Histopathological examination showed findings of AT/RT. In spite of our recommendation of radiation therapy and chemotherapy, her parents refused further treatment. On postoperative brain computed tomography(CT) scan, subtotal removal state of right frontotemporal lobe mass with marked reduction of mass effect and midline shift were shown. On follow-up radiologic examinations at postoperative 4 months, residual tumor was grown and hydrocephalus was progressed aggressively. AT/RT of the cerebrum is an extremely rare and aggressive tumor of early childhood. We suggest that aggressive management may be required even though tumor should be progressed rapidly and shows poor prognosis.
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최병학 ( Byung Hak Choe ),장현수 ( Hyeon Su Jang ),김형섭 ( Hyoung Seop Kim ),문종언 ( Jong Un Moon ) 대한금속ㆍ재료학회 2017 대한금속·재료학회지 Vol.55 No.10
Age hardening and re-crystallization softening of a type of high entropy alloy, CoCrFeMnNi, was performed to investigate the relationship between microstructure and the property of mechanical hardness. Equiatomic CoCrFeMnNi was produced by casting followed by homogenizing, cold rolling and post heat treatments. TEM analysis revealed that the microstructure of the as-rolled alloy was composed of elongated grains with twin laths and a shear band with fine grains, which exhibited a hardness of 371 HV. Following a 500 ℃ heat treatment the microstructure was composed of nano-twins and nano-grains, which represented age hardening, with 454 HV hardness. The microstructure of 700 ℃ heat treated samples was composed of re-crystallized grains and annealing twins, which represented annealed softening, with 244 HV hardness. The 700 ℃ heat treatment also produced spherical particles of 0.1 m maximum grain size, identified as Cr<sub>23</sub>C<sub>6</sub> type carbide. †(Received March 13, 2017; Accepted May 22, 2017)
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