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      • KCI등재SCOPUS

        난관근위부폐쇄의 비개복적치료에 있어서 자궁경관을 경유한 난관의 카테터삽입술의 의의

        노성일(SI Rho),강서옥(SO Kang),권혁찬(HC Kwon),조정현(JH Cho),박종민(JM Park),이승재(SJ Lee),이도연(DY Lee),조병제(BJ Cho) 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.7

        The obstruction of the proximal fallopian tube occurs in 15% of hysterosalpingograms(HSG) performed for infertility. Conventional HSG or laparoscopy may not differentiate the cornual spasm or other temporary causes from true occlusion. We used the transcervical cannulation of the proximal fallopian tubes with a 3-F teflon catheter and a flexible guidewire, 0.015 inch(0.038 cm) in diameter muder the hysteroscopic or fluoroscopic guidance to evaluate and treat the patients with proximal fallopian tube obstruction. Fifty eight patietns with obstructions of the proximal portion of one or two fallopian tubes based on a hysterosalpingogram or a laparoscopic examination were selected for the procedure. Twelve patietns found to have patent oviducts by the selective salpingogram & the selective chromopertubation were therefore excluded from this study. Tubal patency of at least one fallopian tube was achieved in 27 patients(51 tubes), as demonstrated by hysterosalpingogram immediately after the transcervical cathterization procedure. The success rate of recanalization was 62.5%(35/56 tubes) under fluoroscopy and 66.7% (16/24 tubes) under hysteroscopy. In a mean follow-up of twelve months (range: from 8 months to 17 months), eight women with patient tubes after the procedure became pregnant. We conclude that transcervical catheterization appears to represent a useful, less invasive and safe technique to achieve patency in selected cases of proximal tubal obstruction.

      • KCI등재

        특별한 혈소판 감소성 자반증에 합병된 만삭임신 1 예

        한원희(WH Han),노성일(SI Rho),유국영(KY Yoo),노경병(KB No),이훈(H Lee),김은주(EJ Kim) 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.1

        ITP에 합병된 만삭임신에서 감마글로부린을 정맥주사하여 혈소판 수를 증가시킨 후, 제왕절개술을 성공적으로 시행한 1예를 체험하였기에 이를 문헌 고찰과 함께 보고하는 바이다 Idiopathic thrombocytopenic purpura may cause hemorrhagic complications in pregnant women, and transplacental transfer of IgG platelet autoantibodies often leads to neonatal thrombocytopenia Early splenectomy, corticoids and plasma exchange have all been used to provoke remission, and elective cesarean section is often recommended Infusion of high dose intravenous immunoglobulin is a new measure in treating ITP for reversal of platelet count with little side effect We report our experience with this agent in a pregnant woman with ITP and performed cesarean section safely

      • KCI등재SCOPUS

        경질초음파를 이용한 다태임신의 선택적 유산

        민응기(EG Min),이승재(SJ Lee),노성일(SI Rho),박종민(JM Park),전종영(JY Jun) 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.3

        The induction of grand multiple gestation is a known complication of infertility treatment. Various studies show that the incidence of multiple gestation as a complication of induced ovulation therapy in infertile patients ranges from 16% to 39%. Although there is a good deal of information about the gestation of twins, there is very little on triplets, and virtually nothing but case reports have been published on pregnancies involving four or more fetuses. There are so many complications as high fetal and neonatal mortality rate(31% in triplets, 43% in quadruplets and 91% in sextuplets), abortion, preterm labor, pregnancy-induced hypertension, premature rupture of membrane, post-partum hemorrhage, anemia and so on. Without any intervention, an extremely poor prognosis could be expected for viable pregnancies in the multiple gestation. Thus, we believed that an attempt to reduce the number of fetuses to a manageable number was the best possibility for a successful pregnancy outcome. We performed the selective termination (selective reduction) at first trimester (6 to 13 weeks of gestation) for 10 patients, 9 treated with human menopausal gonadotropin and 1 occurred naturally. Using the transvaginal sonoraphy, we carried out cardiac puncture in all cases, and after then, we injected the air into the fetal heart in five cases, injected the KCI solution in three cases and exanguinated the intracardiac blood in two cases. In 5 of the 10 cases, the pregnancies continued to near term without problems and resulted in the delivery of healthy babies. In 3 of the 10 cases, the pregnancy continued without problems for more than 20 weeks of gestation. Septic abortion was occurred just after procedure in 1 case and spontaneous incomplete abortion was developed 4 weeks after procedure in another 1case.

      • KCI등재

        한국인 선천성 이상질환이 의심되는 환자에 대한 세포유전학적 연구

        김진경(JK Kim),양영호(YH Yang),황동훈(DH Hwang),노성일(SI Rho),조주연(JY Cho) 대한산부인과학회 1982 Obstetrics & Gynecology Science Vol.25 No.1

        1974년 1월부터 1980년 5월까지 연세대학교 의과대학 부속병원 산부인과 유전학 연구실에서 선천성 이상이 의심되는 환자 428명에 대하여 세포유전학적 연구를 시행하여 다음과 같은 결과를 얻었다. 1. 다운증후군이 76예였으며 21번 염색체의 3배성이 69예, 모자이시즘이 7예였다. 2. 터너증후군이 13예였으며, 45,X가 7예, 모자이시즘이 6예였다. 3. 클라인펠터증훈군이 17예였으며, 47,XXY가 14예, 46,XY/47,XXY가 2예, 48,XXYY가 1예였다. 4. 원발성무월경이 62예였으며, 60세에서 46,XX,2예에서는 46,XY를 나타내었다. 5. 간성이 75세였으며 정상 염색체양상을 나타내었다. 6. 뇌성마비아동이 98예였으며, 정상 염색체 양상을 나타내었다. 7. 생식기관이외에 선천성 기형이 있었던 경우가 81예였으며 모두 정상 염색체 양상을 나타내었다. 8. 에드워드증후군이 1예 있었으며, 46,XY,+18염색체 양상을 나타내었다. 9. Cri du Chat증후군이 1예 있었으며, 46,XX,5P-의 염색체 양상을 나타내었다. 10. 기타 종질중격과 중복자궁이 각각 2에씩 있었으며, 정상 염색체양상을 나타내었다. As the cytogenetics developed, cytogenetic study in Korea has also developed progressively. However, cytogenetic studies in Korea were merely studies on normal chromosome pattern or simple studies of several genetic disorders or cases reports. This study is a systematical cytogenetic analysis of 428 cases where congenital disorders were suspected and referred to our cytogenetic laboratory in the Department of Obstetrics and Gynecology, Yonsei University Medical Center, from Jan. 1974 to May 1980. The results were as follows; 1) Downs syndrome was found in 76 cases, consisting of 69 cases(90.79%) of primary 21 trisomy and 7 cases of mosaicism. 2) Turners syndrome was found in 13 cases, consisting of 7 cases(53.85%) of 45,X and 6 cases of mosaicism. 3) Klinefelters syndrome was found in 17 cases, consisting of 14 cases(82.35%) of 47,XXY, 2 cases of 46,XY/47, XXY and 1 case of 48,XXYY. 4) Primary amenorrhea was found in 62 cases, consisting of 60 cases(96.78%) of 46,XX and 2 cases of 46,XY. 5) Intersex was found in 75 cases, consisting of 45 cases(60%) of 46,XY and 30 cases of 46,XX. 6) Cerebral palsy was found in 98 cases and all cases were normal karyotype. 7) Congenital anomalies excluding the reproductive organ was found in 81 cases were normal karyotype. 8) Edward syndrome was found in 1 case, karyotype was 46,XY, +18. 9) Cri-du Chat syndrome was found in 1 case, karyotype was 46,XX, 6P-. 10) Longitudinal vaginal septum and double uterus were found in 2 cases each and all cases were 46,XX.

      • KCI등재SCOPUS

        Polymerase Chain Reaction을 이용한 태아 Y염색체의 검사

        강성호(SH Kang),정규병(KB Jung),한호원(HW Han),김영철(YC Kim),노성일(SI Rho),오기석(KS Oh),한인권(IG Han),문인걸(IG Moon) 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.3

        Prenatal fetal sex determination is very important in the management of X-linked genetic disorders. The polymerase chain reaction with Y-chromosome specific DNA sequence is available. We have performed 16 fetal sex determination using the polymerase chain reaction and karyotyping method with samples of chorionic villi and amnionic fluid. We have correctly determined fetal sex within 6 hours by the polymerase chain reaction. Thus the polymerase chain reaction is a reliable method to determine fetal sex rapidly in the X-linked disorders.

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