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김학봉,임경호,나기웅 한국 항공대학교 항공산업기술연구소 1996 航空宇宙産業技術硏究所 硏究誌 Vol.6 No.-
항공기 착륙장치 완충기내 유압유의 유동특성을 비정상, 비압축성 점성 유동방정식을 일반 곡선 운동좌표계에서 수치적인 방법으로 해석하였다. 수치 방정식은 일반적으로 그 특성이 잘 알려진 SIMPLE 방법으로 해석하였다. 해석된 결과는 오리피스를 지나는 정상유동에 대한 실험 유량계수와 비교함으로서 점검하였다. 두 가지의 동역학적 문제에 대하여 계산하여 실제 낙하시험 결과와 비교하였다. 모든 경우에 합리적인 결과들를 얻을 수 있었다. In this study, the flow characteristics of hydraulic oil in the shock absorber of aircraft landing gear is analyzed using numerical method for the unsteady incompressible Navier-Stokes equations in generalized moving coordinates. The discrete equations are solved by the SIMPLE method. The results are validated by comparing the discharge coefficient of an orifice with experimental results for the steady flow through it. two dynamical cases are computed and compared with an actual landing gear drop test. The obtained results are reasonable in all cases.
Hep G2 세포에서 간염제1탕의 에탄올에 의한 세포독성 억제효과
박용권,김강산,강병기,나기웅,Park, Young-Kweon,Kim, Gang-San,Kang, Byung-Ki,Ra, Ki-Ung 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.1
Object : Hepatitis Treatment-tang No.1 has been used for the treatment of Liver disease and Jaundice. Long-term EtOH exposure leads to immunoregulatory and detoxification impairment. This study aimed to determine the relationship between TNF-${\alpha}$ production and expression, and EtOH-induced cytotoxicity on Hep G2 cells. Method : Cells were incubated with EtOH in the presence or absence of HT. The cells were tested after 24 hours and, again, after 48 hours. Cytoviability and TNF-${\alpha}$ release were analyzed by MTT assay and enzyme linked immunosorbent assay (ELISA), respectively. After 24 hours of EtOH exposure, the cytoviability decreased, and the release of TNF-${\alpha}$ was increased. Increased amounts of TNF-${\alpha}$ contribute to EtOH-induced cytotoxicity. The Anti-TNF-${\alpha}$ antibody almost abolished it. Interestingly, EtOH-induced cytotoxicity and TNF-${\alpha}$ production were inhibited by HT. Moreover, when HT was used in combination with the anti-TNF-${\alpha}$ antibody, there was a marked inhibition of EtOH-induced cytotoxicity. Results : These results suggest that HT may prevent the cytotoxicity through partial inhibition of the TNF-${\alpha}$ secretion.