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- 저자 : 김철성(CS Kim) (검색결과 6 건)
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김철성(CS Kim),김성기(SK Kim),송승규(SK Song),김승조(SJ Kim),신경섭(KS Shin) 대한산부인과학회 1975 Obstetrics & Gynecology Science Vol.18 No.11
Pelvic Angiography is simple and safe procedure, may be of great help in early diagnosis and management of gynecologic lesions, especially malignant trophoblastic neoplasms. Malignant trophoblastic neoplasm is a relatively common disease in Korea as other countries. We have attempted to analyze the pelvic angiographic findings in 15 patients. who were 6 cases of trophoblastic disease, 6 cases of cervical cancer and 3 cases of other diseases. The results were obtained as follows; 1. Malignant trophoblastic neoplasms were found more typical changes consisting of opacified irregular vascular spaces with early draining vein, pooling of contrast medium around central avascular areas, displacement of vessels by tumor masses and persistnet stains 2. By pelvic angiography it is valuable diagnostic procedure to make an early diagnosis of choriadenoma destruens which can not be deteceted by curettage and hCG test. 3. By pelvic angiography the metastatic lesion and location can be detected in cervical cancer over clinical stage III.
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김철성(CS Kim),공원보(WB Kong),나종구(Rha CG),전정일(CI Chun) 대한산부인과학회 1974 Obstetrics & Gynecology Science Vol.17 No.6
본 교실에서는 일난성쌍태아 중 일측에 정상아와 다른 일측에 무뇌아를 동반한 1예를 경험 하였기에 간단한 문헌의 고찰과 함께 보고하는 바이다. This a case report that 31 year old woman who had twin pregnancy, which one was anencephalus, the other one was normal. Authors a brief review of literatures was made.
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항HCG B-Subunit 혈청을 이용한 혈중 융모성 성선자극호르몬의 특이방사면역측정
김승조(SJ Kim),최성기(SK Choi),김철성(CS Kim),김응호(YH Kim) 대한산부인과학회 1975 Obstetrics & Gynecology Science Vol.18 No.7
항 hCG B-subunit혈청을 융모성 성선자극호르몬의 방사면역 측정에 이용하여 일반 단백호 르몬의 방사면역 측정이 갖는 교차반응을 극복할 수 잇는 특이 면역측정법에 대한 검토를 한 바 다음과 같은 결론을 얻었다. 1. 125 I-hCG와 표지하지 않는 hLH를 여러항 혈청에서 경쟁결합시킨 결과 항 hLH Batch 1 혈청과 항 hTSH혈청에서 유의한 교차반응을 보였다. 2. 항 hCG혈청에서 125I-hCG와 표지하지 않은 hCG, 2nd IRP-HMG그리고 hLH를 경쟁결합 시킨결과 상호 교차 반응을 관찰할 수 잇었고 hCG와 2nd IRP-HMG는 거의 유사한 결합반 응을보였다. 3. 항 hCG B-subunit혈청에서 125 I-hCG와 표지되지 않는 hLH, 2nd IRP-HMG, hCG 그리고 hCG B-subunit를 경쟁결합 시켰을 때 특이 결합반응을 hCG, hCG B-subunit에서 관찰할 수 있었다. 4. 항 hCG B-subunit 혈청을 이용한 hCG의 방사면역 측정을 소수의 환자에서 시행한 결과 항 hCG 혈청을 이용한 환자의 혈청중의 hCG보다 낮은 수치를 보엿고 특이 측정이 된 것을 볼 수 잇었다. 5. 이상으로서 좀더 hCG B-subunit에 대한 연구가 진척되면 교차반응을 감별할 수 잇는 특 이 방사면역 측정법이 개발되리라 생각된다. Assay of glycoprotein hormones have wide and numerous applications in research of human reproduction and clinical practice. Because it is cheaper, easier to replicate, and more sensitive, immunoassay is rapidly replacing bioassay for these human hormones in research and in clinical practice. Radiommunoassay varies widely in their degree of specificity for different molecular forms, so the specificity of assay systmes for each hormone should be rigorously assessed. The problem is especially complex with the glycoprotein hormones because of their close structural similarity . Recent researches reveal that the a-subunit, comprising about half the molecule of pituitary FSH, TSH, LH and hCG are very similar to each other for these hormones. Hence one method might be the use of a specific antiserum to the B-subunit of hCG, which would react with both the B-subunit and intact hCG, but not with LH. 1. Binding of 125I-hCG after iodination with anti hCG serum were 23.34+-1.62% at the 3rd week, 13.66+-1.02% at the 4th week, and 6.90+-1.11% at the 6th week. 2. In the displacement study of 125 I-hCG unlabelled hormones from anti-hLH and anti-hTSH sera native hCG cross-reacted with both antisera. 3. Antisera to the B-subunit of hCG discriminated hCG from hLH and hMG while most of antisera produced by immunization with intact hCG did not. 4. None of glycoprotein hormones preparation tested cross reacted at physiological levels in the patients by the hCG B-subunit radioimmunoassay system. The development of that radioimmunoassay and some applications will reflect the potential clinical usefulness of the specific hCG radioimmunoassay.
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신재진(JJ Shin),이영순(YS Lee),김철성(CS Kim) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.10
A Case of uterus Didelphys Associated with unilateral imperforate vagina is reported with a review of the literature. In this case ipsilateral renal agenesis was found on the affected side. A synopsis of the embryologic defect responsible for the development of this anomaly and the recommended management of the disorder are outlined.
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조창묵(CM Joe),조헌성(HS Cho),김철성(CS Kim),오원섭(WS O) 대한산부인과학회 1980 Obstetrics & Gynecology Science Vol.23 No.9
There are many causes of bleeding during the latter half of pregnancy with life threatening situation of mother and fetus. Abruptio placentae is the separation of a normally implanted placenta after the 20th week of gestation and before the birth of fetus, so it is one of most serious complications in pregnancy in dealing with maternal and fetal mortality in our country. Several series in the literature suggest that an abnormal fetal-maternal relationship exist in patients with abruptio placentae weeks prior to the actual placental separation and that separation is the only the terminal events. The data presented here are based on the 140 cases of abruptio placentae among 10187 deliveries at the Department of Obstetrics and Gynecology, Han Gang Sung Shim Hospital in Seoul, from January 1, 1974 to December 31, 1979. 1) The incidence of abruptio placentae was 1.37% or one in 73 deliveries. 2) The majority of abruptio placentae occured between age 25 and 29, and its percentage was 38.6%. 3) The incidence of abruptio placentae in nulliparous woman was 31.4% and in multiparous woman was 68.6%. 4) The majority of abruptio placentae occured between 35 and 39 weeks of gestational age. It was interesting to identify that more than half(57.1%). 5) Abruptio placentae was associated with preeclampsia and other hypertensive disorders in 48.6% and unknown causes in 50.7%. 6) The most common symptom in our studies was abdominal pain and tenderness(82.1%). Vaginal bleeding was found in 69.3% and intrauterine fetal death in 60.7%. 7) Perinatal mortality had close relationship with duration from onset of abruptio placentae to delivery. If the duration was more than 6 hours, perinatal death was occured more than three quaters of baby. 8) The amount of transfusion in total abruptio placentae was about 2600cc in average and about 1100cc in partial abruptio placentae. The maximum amount of transfusion was 10800cc. 9) Cesarean section was performed in 46.4%, vaginal delivery in 42.9% and cesarean hysterectomy in 10.7%. 10) The complicaions of abrupio placentae in our studies were followed., The frnal failure occurred in 2.9%, shock in 2.9%, coagulation defect in 2.1% and postpartum henorrhage in 2.1%. 11) Perinatal mortality rate was 72.9% including still birth (60.7%) and neonatla death (12.2%). The rate was 75.0% in vaginal delivery and 71.3% in cesarean section. Maternal mortality rate was 0.7% of total cases.
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