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김욱천,김유신,한상화,Kim, Uk Cheon,Kim, Yu Sin,Han, Sang Hwa Korean Chemical Society 2000 Bulletin of the Korean Chemical Society Vol.21 No.4
Association of cytochrome c with anionic membranes involved both electrostatic and hydrophobic interactions and their relative contributions depended on the physical state of the membrane and the redox state of cyto-chromec.Hydrophobic interaction was favored by the membranes in gel phase, by the membranes with a large curvature, and by the membranes with a high surface charge density. Ferrocytochrome c was less dissociable by NaCl than ferricytochrome c suggesting that a lower protein stability is beneficial for hydrophobic interac-tion.Hydrophobic interaction induced larger structural perturbations on cytochrome c as monitored by the loss of the Fe-Met bond and by the increase in the distance between heme and Trp-59. When bound to anionic mem-branes,spin-labeled cytochrome c showed an electron paramagnetic resonance spectrum with two or more components, providing a direct evidence for multiple conformations of bound cytochrome c.
rhBMP-2를 이용한 상악동거상술의 성공적인 치료 전략
김현철(Hyoun Chull, Kim),김수남(Soo Nam, Kim),이장렬(Jang Yeol, Lee),김욱천(Uk Cheon, Kim) 대한치과의사협회 2015 대한치과의사협회지 Vol.53 No.1
BMPs are multi functional growth factors which are members of the transforming growth factor beta super family and their ability is that plays a pivotal roll in inducing bone. About 18 BMP family members have been identified and characterized. Among of them, BMP 2 and BMP 7 have significant importance in bone development. In this case reports, patients of maxillary sinus graft were received who visited LivingWell Dental Hospital. We focused on the results of the surgical intervention. We suggest that new strategy of treatment used to rhBMP 2 and TCP scaffold for patients of sinus graft. The purpose of this paper is to give a brief overview of BMPs and to critically review the clinical data currently available on rhBMP 2 and synthetic bone scaffold.