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습관성 유산 환자에 있어서의 Toxoplasma 항체가
김생기(SK Kim),정채득(CD Jeong),오병찬(BC Oh),김종덕(JD Kim) 대한산부인과학회 1984 Obstetrics & Gynecology Science Vol.27 No.6
A prospective study of 110 obstetric cases was done to find out the role of toxo- plasmosis in abortion. The subjects comprised 15 habitual abortion, 35 sporadic abortions and 60 normal pregnancy cases were investigated for toxoplasmosis by dye test and by mouse inoculation with gestational materials. In no case, could Toxoplasma gondii be isolated from the pregnant endometrium by inoculation. The dye test was positive in 80 per cent of habitual abortion and 62.7 per cent of spo- radic abortion respectively. In normal pregnancy as the control postives result were pregnancy and abortion were significnat particularly in habitual abortion. These findings suggest that toxoplasma may prove an important etiological factor for spontaneous abortion.
Isoproterenol이 백서 자궁수축에 미치는 영향
김영인(YI Kim),김생기(SK Kim),이춘근(CK Lee) 대한산부인과학회 1983 Obstetrics & Gynecology Science Vol.26 No.11
Pharmacological analysis of the inhibitory effect of isoproterenol on the pregnanr and non-pregnant strips of rat uterus, and isoproterenot induced desensitization has been made on the basis of 봭-adrenergic receptors. 1. Inhibitory effect of isoproterenol in the pregnant uterus was greater than in the non-pregnant uterus, while the rate of spontaneous contraction was higher in the non-pregnant uterus. 2. Inderal inhibited the inbibitory effect of isoproterenol in both preparations, resulting in the parallel shifts of does responsive curves to the right. 3. Isoprotereno1-induced desensitization. 4. Isoprotereno1-induced desensitization was not prevented by the treatment of isoprotereno1, inderal or pyrogallol. From the above result, it is suggested that difference of inhibitory effect of isop roterenol in the non-pregnant uterus and in the pregnant uterus, and isoproterenol induced desensitization were not due to the alteration of β-adrenergic receptor.